Protein Info for mRNA_6741 in Rhodosporidium toruloides IFO0880

Name: 15109
Annotation: K01657 trpE anthranilate synthase component I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04715: Anth_synt_I_N
  • amino acids 41 to 176 (136 residues), 93.3 bits, E=1.6e-30
• PF00425: Chorismate_bind
  • amino acids 250 to 506 (257 residues), 294.2 bits, E=9.8e-92

Predicted SEED Role

"Anthranilate synthase, aminase component (EC 4.1.3.27)" in subsystem Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. or Tryptophan synthesis (EC 4.1.3.27)

MetaCyc Pathways

• superpathway of aromatic amino acid biosynthesis (16/18 steps found)
• superpathway of L-tryptophan biosynthesis (12/13 steps found)
• L-tryptophan biosynthesis (5/6 steps found)
• 4-hydroxy-2(1H)-quinolone biosynthesis (2/5 steps found)
• acridone alkaloid biosynthesis (1/4 steps found)
• superpathway of quinolone and alkylquinolone biosynthesis (2/10 steps found)
• superpathway of chorismate metabolism (28/59 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of phenylpropanoids
• Biosynthesis of plant hormones
• Phenylalanine, tyrosine and tryptophan biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.3.27

Protein Sequence (531 amino acids)

>mRNA_6741 K01657 trpE anthranilate synthase component I (Rhodosporidium toruloides IFO0880)
MPPNLSHTLPEVLSLLLPSSSSSSPSPAGNCLPIWSTLPADVLTPVIVYLRLTDGAKNGE
SFLLEGAVKGETAGRWSYVGAGPKEVYRSGPGQDLGAVDPLKPLEKNLSKYKFIKVHGAP
PFTGGAIGYVGYDCIHYFEPKTARSDLSDPMGIPESVWLLHDTIVAFDHLFQRVYVVSHV
YLPDSSASESTIQASYDDAVKNIDAVLAKLLSTAPLPLPEQPPVTSAPIPANEKPEERYA
RLDKMSNVGKEGYERFVTSLKGSIVQGEIIQAVPSQRLRRETKLHPFNVYRHLRQLNPSP
YMFYINCGNGTQLVGASPECLCKVEEGGKVTNHAIAGTVRRGKTPAEDAALAAELSASMK
DRAEHVMLVDLARNDVNRVCKPETVVVDSLMQVEKFSHVMHLTSQVSGLLREGQTRFDAF
RSIFPAGTVSGAPKIRAIELISALELERRGVYAGAVGHFDFSSESMDTCIAIRTMVFKDG
VAFLQAGGGIVFDSVEEDEYVETVNKLGANVRCLEEAEAYYAALQAEQRQA