Protein Info for mRNA_6791 in Rhodosporidium toruloides IFO0880

Name: 15159
Annotation: K00888 PI4KA phosphatidylinositol 4-kinase A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1800 1907 transmembrane" amino acids 641 to 663 (23 residues), see Phobius details amino acids 838 to 860 (23 residues), see Phobius details PF00613: PI3Ka" amino acids 1401 to 1531 (131 residues), 73.6 bits, see alignment 1.4e-24 PF00454: PI3_PI4_kinase" amino acids 1648 to 1851 (204 residues), 106.3 bits, see alignment E=2.5e-34

Best Hits

Predicted SEED Role

"Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67)" (EC 2.7.1.67)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.67

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1907 amino acids)

>mRNA_6791 K00888 PI4KA phosphatidylinositol 4-kinase A (Rhodosporidium toruloides IFO0880)
MDYLDGNLHQSLLTALAANLASTSEQDDLALLTTSFSSLEPVSNTAIHGVLSRMNGAYGA
GEGELVTNDQLEGMIAFAEYSSSAEHNQAQAGQVVKLLQGIPRWSLEPALGVQASYDWAP
ADRLSFALTDAAFRCADLNGQAREAVIKSVQFVQAELERQARDAPGPRTISYVLPALNGL
RRAIPQGHLRWTAADPQPSILSFDDPAVTHLRSIFANSSDLDLSSEEGRIALATLEKYQF
IQPGLSPTLPLLASLEIQQAYWSSFLSAAKTSDARWKEMLVGSGKQTDKSAMPQQIAAEG
VAQKALEIWQRVVRAIENEDEMDDEVDLQPTPLLVASLTLAVTASVVARKLEPDLLGILE
SVLHPESAGIDESIQVAGSQALQVIAHGFPERLTSATEIIRRFLLSPALRPSDDPSTLTP
ALQTATEAYSALLARSDSSSRTSAIQTLLNHLASIERQGHVPNGDSFVDAASTIGSVRRY
GGDTAEVAANIVHVVSLLARKSGETSLTRLVGSTLLHYAMNGSVLVQCAALIELREIAAV
SDKHAYVESLRTVTGVARTATGGDDISYQTAISALTQLASIAAKKHEELGFSFLSELLTL
FGNKGAESAGSSEERTQMLLALVAVLDSYLTQVSFDASSVISSALGALFRGFWYTCLLSG
FLSSPQRLSAWQRGALLSVAKRSPPLVVSVSQDLVELEAQVQAILKSASSHSMSVEAIRG
DLANGIPSQATHARSISAPQAVFLTTAYRLESLRAEAGAIAPLFLYFGVPALSGESAVGD
TLKSIGDKVLSVYMARLGQQVPLHAMDSSAYVQVRTILLHTTNSSESMRSTALRFLDNIL
ASFPSLVCNLGVVTVMLELLTVLRRACLDEFTDEYTPSFEFHSTRGNFTITLSDDYPLRN
RILRNLHEHVRSWLKKGITRSPLEMQGLLQEYVDVTSDGYRMQMLNDDEMGKSVALDLVK
TPPANGKYASLPAWGNWNADASTAFARTFAAKSFFGGEVQRGATNPRDVLDKLEDLAEQL
DKHKLHFKLSELRDLFYRGAAQVVKAQQPDFEVLRHVVSLPVRLYTEASIAVGQEIWTWI
ADARPELEPRVVSEVLEAWADAIEREQGLFSRTLDNDTPLNQETQFTPTDKEALNRDYLF
ANRLFSPMLAMLDFLQSRYQAYRYRNADLVYATLRLLLRTLEAHENWSRHPLSRELRLTL
LSFGFTLIGGSRLDSIAEYNLRAKLFDAAFAWFEVRPTWSFGNNRIQIKADLQAIDNLLQ
AVQADSPNYDVVSSSFEDSRLAPVLPDRASASSAKEAQRLRQQLLKALLSDEAERLRLWL
NPLLDSKRGAVPTGETPGVEELRKLARFAWTRWPKVVVFLHERFKLPPLLEEVVRVIRSD
PLAVQDCPDALPLFVGESLSLESRSKFRHLLYWAPVPVPEALRFLFPKFGGDPILLQYAL
RVLEHHPVAITFFYVPQVVQALRTDELGYAERFIFETSKISQLFCHQIIWNMKANAYRGD
DAEEADPMKPKLDRLVDMIVESLSGEAQDFYNREFTFFDEVTSISGKLKPFIKSPKPEKK
AKIDEEMAKIKVDVGVYLPSNPDGVVVDINRTSGRPLQSHAKAPFMATFKVRRTRHTADT
DDLEAQDELIDVEEGAASSRKQEYDTWQSAIFKVGDDCRQDVLALQIVAMHKNIWNSLGL
DLLVTPYRVTATGPGMGVIDVIPNATSRDEMGRAKINDLLSFFKMKFGPVESADFQRARN
HFIQSMAAYSVLCFIIQIKDRHNGNIMVDAKGNIVHIDFGFLFDIGPGGVKFEPSSFKLT
HEMLTLMGGKDSVGYRHFKELTVKAFLAARPYAQSIVDTVALMLAAEFPSFKGEPTLERL
KGRFRLDLSEKKAAEWWLTIVDDACENKRSIVYDEFQRITNGIPYVR