Protein Info for mRNA_6820 in Rhodosporidium toruloides IFO0880

Name: 15188
Annotation: K00931 proB glutamate 5-kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01027: glutamate 5-kinase
  • amino acids 6 to 392 (387 residues), 346.8 bits, E=7.8e-108
• PF00696: AA_kinase
  • amino acids 6 to 245 (240 residues), 132.4 bits, E=2.2e-42

Predicted SEED Role

"Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA" in subsystem Proline Synthesis (EC 2.7.2.11)

MetaCyc Pathways

• superpathway of L-citrulline metabolism (10/12 steps found)
• L-citrulline biosynthesis (7/8 steps found)
• L-proline biosynthesis I (from L-glutamate) (4/4 steps found)
• L-ornithine biosynthesis II (3/4 steps found)
• L-N^δ-acetylornithine biosynthesis (5/7 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.2.11

Protein Sequence (508 amino acids)

>mRNA_6820 K00931 proB glutamate 5-kinase (Rhodosporidium toruloides IFO0880)
MVHPLTVVIKLGSSSILHPEPPHFPQIATLSALAETCVSLRALGHRVVIVSSGAIGMGLH
RMELPTLAPGKKRAIGEKQALAAIGQGRLIALWDQIFGALKQPIAQILLTRNDIADRSRY
LNATTTLSTLLSLGVIPIINENDTVSVSEILHVNKFGDNDTLSAIAAGMCGADYLFLMTD
VDGLYEDNPRRVPGARRVAKVRDIEEVRRLVSTSTLGSSLGTGGMETKLIAAELATAAGC
ATVITMGSMPTRILTIVQGHNSRTAPPSPTSSSTASLQPISEISASPPSAHVSNRPGVEF
ASPTDDSVPPHTLFMPKTSPLSSRRFWILHGLTPRGTVFVDEGAYRAITRGERDGGGGGN
GGRLLAAGVLRVEGTFAAGQAVRVCVVLKKGANKERGRSASRKDGRVPSRARSPDHFADR
SSEREEKERELARAAEGLSLRDVAAAEKAQKAKEDAEEVIEFGRGLTNYNSVEIDRVKGL
RSSDIEKVIGYFEAEHVVESICEVKRTT