Protein Info for mRNA_6859 in Rhodosporidium toruloides IFO0880

Name: 15227
Annotation: K16794 PAFAH1B1, LIS1 platelet-activating factor acetylhydrolase IB subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 PF00400: WD40" amino acids 105 to 139 (35 residues), 26.9 bits, see alignment 1e-09 amino acids 146 to 181 (36 residues), 30.1 bits, see alignment 9.9e-11 amino acids 186 to 223 (38 residues), 32.6 bits, see alignment 1.6e-11 amino acids 230 to 266 (37 residues), 31.5 bits, see alignment 3.5e-11 amino acids 310 to 333 (24 residues), 16.2 bits, see alignment (E = 2.4e-06) amino acids 337 to 375 (39 residues), 39.9 bits, see alignment 7.7e-14 amino acids 379 to 442 (64 residues), 20.1 bits, see alignment E=1.4e-07 PF12894: ANAPC4_WD40" amino acids 330 to 399 (70 residues), 28.9 bits, see alignment E=1.8e-10

Best Hits

Swiss-Prot: 65% identical to LIS1_USTMA: Nuclear distribution protein PAC1 (PAC1) from Ustilago maydis (strain 521 / FGSC 9021)

KEGG orthology group: K01062, 1-alkyl-2-acetylglycerophosphocholine esterase [EC: 3.1.1.47] (inferred from 65% identity to uma:UM03164.1)

Predicted SEED Role

"High-affnity carbon uptake protein Hat/HatR" in subsystem CO2 uptake, carboxysome or Carboxysome

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (444 amino acids)

>mRNA_6859 K16794 PAFAH1B1, LIS1 platelet-activating factor acetylhydrolase IB subunit alpha (Rhodosporidium toruloides IFO0880)
MTSVLSERQKDELHKSILDYLRTNGFTETLNAFKAEAKQEDFQPDGKAKWSGLLEKKWTS
VIRLQKKIMDLETRNSQLQEELSTAPSKRPSASSPDWTPRTPARHSLSGHRSPVTRVTFH
PLFSVVVSASEDSTLKVWDWETGDFERTVKGHTKAVQDVDFDSKGNLLVSCSSDLTIKLW
DTNNDWKNIRTLHGHDHSISTARFLPNDDFIVSASRDRTIRIWEVASGFCTRTISGHNDW
VRSVLPSSDGQQLISCSVDQTARIWDLGKGDTKAELRGHEHVIEAAVFAPVAAYPAIREL
AGMTVPSGRSAEAKAVGLFAATGSRDKTIKIWDAVSGQCLKTLVGHDNWIRALVFHPSGK
FLLSASDDKTIRTWDLATGRCLKTLEAHSHFVTTMAWGRAPAPGASQPNGAATNGTNGAH
AEAARLVNVVATGSVDQTVKIWLP