Protein Info for mRNA_6870 in Rhodosporidium toruloides IFO0880

Name: 15238
Annotation: K08736 MSH3 DNA mismatch repair protein MSH3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1205 transmembrane" amino acids 869 to 891 (23 residues), see Phobius details amino acids 953 to 971 (19 residues), see Phobius details PF01624: MutS_I" amino acids 236 to 348 (113 residues), 89.4 bits, see alignment E=5e-29 PF05188: MutS_II" amino acids 363 to 464 (102 residues), 43.6 bits, see alignment E=9.5e-15 PF05192: MutS_III" amino acids 570 to 887 (318 residues), 124.7 bits, see alignment E=1.4e-39 PF05190: MutS_IV" amino acids 759 to 841 (83 residues), 31.6 bits, see alignment 4.3e-11 PF00488: MutS_V" amino acids 940 to 1129 (190 residues), 209.6 bits, see alignment E=1.1e-65

Best Hits

Predicted SEED Role

"DNA mismatch repair protein MutS" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1205 amino acids)

>mRNA_6870 K08736 MSH3 DNA mismatch repair protein MSH3 (Rhodosporidium toruloides IFO0880)
MPPKKAEDGSQQSISSFFSRAPVPQKRESVLVLDSSDEDEEVKDEAGRGGKAAQGVKRVK
TEHDSRDSQLQPIASTSKLPTPATYPPRDPQSPSSQRLRQFAYSQPDPSASKPPSRPSAA
DQARHDAFVKKLSLGPDLLKRRTSYLQKEHYLAARDDDADGEGSPAGGLGSPGMLAEDLE
EDAETDSSSNSTPARAKGKGKAKATESDDMPSLLAKFAAKGSNAGGKGSSKKVKYTPLEQ
QVLALRKAHPGVLLVIEVGYKFRFFDEDAQVASRILNIACFSSQHMLTASIPTHRLDVHV
KRLLNAGYKVGVVRQQETAALKKASDNRSAPFTRALSALYTSATYVDELGVDPLSTTGST
ATIMCIIEDKLGKAPDAKVKIGMVAVVPATGQVVYDEFEDGLMRSELETRMLHLQPSELL
LQEELSSKTESMVQHLVGQHNAGTADFRSRIDRISKRPSASQATSQISDYLASVKKREKG
KEKASSGKALRKEPSEIVLSSGDEGEGADTEISRAALNGSVAILDLPKLVLIALASLLSH
LKPFNLDNVFSHTSSFTPFASRASMNLNGNTVANLELLRNNTDFKEHGSLIACIDKCKTA
MGGRLLRKWLTKPLLSKELVEERLDAISDIHRLSTSLTLSKMRDLLKHLPDLERGLSRIH
FGRATPNELLRVLEAFRRIGDVFVEVDSPDEDNAEAGDDGPIRTGAGGGLRSTLLKSVVK
ELPKVKQTADELLAEVDGKRARDNDKEELFANEDKYPDLKKCKAGLARTIDDMQDELKSA
RKVLRKPALQFTKVAQEEYLFEVKIAEAKTIVPADWIRINSTKQVYRYRSPRLHKMVTET
LEQWKEKVAAAAKAAFHDFLQEVSSHYELFRTIIASVATADCLFGLALVALSNNWVRPTI
VDEPGYIDFVDGRHPIIEDVSPEPFVPNSIKFGGGERRQMVLTGLNMGGKSSLSRMIALI
ALLAQIGSFVPAESCTTSLFDGIYTRMGANDDVARGRSTFMVELTETSEILRLATPRSLL
ILDELGRGTSTNDGQAIAAAVLEYIVRSKRSTCVFVTHYPSLALVAQRFPESVSVNHMAC
IETPREDGHADVTFLYCPADGLASASHGLNVARLADLPQSVLDTAKAKGLELMKETEERT
AKRKAGRLAEILGRVARLAMADEGMGVNDGGPNASQGSATNGMSQGSVGTRRNRLLELCE
AALVK