Protein Info for mRNA_6983 in Rhodosporidium toruloides IFO0880

Name: 15351
Annotation: K02145 ATPeV1A, ATP6A V-type H+-transporting ATPase subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 616 TIGR01042: V-type ATPase, A subunit" amino acids 23 to 608 (586 residues), 1088 bits, see alignment E=0 PF02874: ATP-synt_ab_N" amino acids 26 to 88 (63 residues), 52.7 bits, see alignment E=7.7e-18 PF16886: ATP-synt_ab_Xtn" amino acids 104 to 226 (123 residues), 145.8 bits, see alignment E=8.7e-47 PF00006: ATP-synt_ab" amino acids 235 to 460 (226 residues), 361.5 bits, see alignment E=2.3e-112

Best Hits

Swiss-Prot: 69% identical to VATA_SCHPO: V-type proton ATPase catalytic subunit A (vma1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K02145, V-type H+-transporting ATPase subunit A [EC: 3.6.3.14] (inferred from 76% identity to lbc:LACBIDRAFT_189496)

MetaCyc: 69% identical to H+-translocating V-ATPase subunit A (Homo sapiens)

Predicted SEED Role

"V-type ATP synthase subunit A (EC 3.6.3.14) @ intein-containing" (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (616 amino acids)

>mRNA_6983 K02145 ATPeV1A, ATP6A V-type H+-transporting ATPase subunit A (Rhodosporidium toruloides IFO0880)
MAGAMQNAKKTIRIQDEERESKFGSVFSVSGPVVIAEKMAGAAMYELVRVGHDELVGEII
RIDGDKATIQVYEETSGMTIGDPVLRTGKPLSVELGPGLMSNIYDGIQRPLKAIAEKSES
IYIPRGINTDALDRGIKWDFDPVNFKVGDHIAGGDIFGKVYENSLVSEHKIMMNPRGMGT
VTHIAEKGSYSVEDVVLETEFEGKKTQHTMLQLWPVRAPRPTGEKLEANYPLLTGQRVLD
SLFPCVQGGTTAIPGAFGCGKTVISQAVSKFSNSDIIVYVGCGERGNEMAEVLMDFPELS
IDVNGVQEPIMKRTTLVANTSNMPVAAREASIYTGITLSEYFRDQGRNVAMMADSSSRWA
EALREISGRLAEMPADSGYPAYLGAKLASFYERAGKAVCLGSPRRTGSTTIIGAVSPPGG
DFSDPVTTATLGIVQVFWGLDKKLAQRKHFPSVNWNVSYSNYTRVLQPYYEETEPDFLHY
RNLAKQILQKENELAEIVQLVGKSSLGEEDKVVLDVARLLKEDFLQQNGISTYDRYCPFY
KTTGMLKCMIAYYEAAIKAVDNEGTTWSRVKDATSDLYYRLTQLKFLDPADGQEPIEKEI
NQLHADIQRTFQDLAD