Protein Info for mRNA_7027 in Rhodosporidium toruloides IFO0880

Name: 15395
Annotation: K13025 EIF4A3, FAL1 ATP-dependent RNA helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 PF00270: DEAD" amino acids 48 to 211 (164 residues), 151.4 bits, see alignment E=3.4e-48 PF04851: ResIII" amino acids 49 to 207 (159 residues), 22.5 bits, see alignment E=1.5e-08 PF00271: Helicase_C" amino acids 249 to 357 (109 residues), 112.9 bits, see alignment E=1.6e-36

Best Hits

Swiss-Prot: 88% identical to FAL1_CRYNJ: ATP-dependent RNA helicase FAL1 (FAL1) from Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)

KEGG orthology group: K13025, ATP-dependent RNA helicase [EC: 3.6.4.13] (inferred from 88% identity to cne:CNC06360)

Predicted SEED Role

"Eukaryotic translation initiation factor 4A"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (396 amino acids)

>mRNA_7027 K13025 EIF4A3, FAL1 ATP-dependent RNA helicase (Rhodosporidium toruloides IFO0880)
MSIDAAKDSKLVFETSESVTVAPTFDALGLKEDLLRGIYAYGFEKPSAIQQRAIAPVIKG
RDVIAQAQSGTGKTATFSISMLQSIDSSVRDTQALVLSPTRELATQIQSVVLALGDYMNV
SCHACIGGTSIGEDIRKLEHGQQIVSGTPGRVFDMIKRRHLRTRNIKMLVLDEADELLNR
GFMDQIYDVYRYLPPQTQVVVLSATLPHDVLEMTTKFMTDPIRILVKRDELTLEGIKQFF
VAVEKEDWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTEKMREANFTVSSMHGEMPQKE
RDSIMSEFRSGSSRVLITTDVWARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKG
VAINFVTNDDLKVLRDLEQYYATQIDEMPVNVQEAL