Protein Info for mRNA_7070 in Rhodosporidium toruloides IFO0880

Name: 15438
Annotation: K13953 adhP alcohol dehydrogenase, propanol-preferring

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 PF08240: ADH_N" amino acids 38 to 147 (110 residues), 97.5 bits, see alignment E=6.6e-32 PF00107: ADH_zinc_N" amino acids 190 to 322 (133 residues), 90.8 bits, see alignment E=1.1e-29 PF13602: ADH_zinc_N_2" amino acids 245 to 356 (112 residues), 35.5 bits, see alignment E=3.1e-12

Best Hits

Swiss-Prot: 52% identical to ADH_SCHPO: Alcohol dehydrogenase (adh1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K13953, alcohol dehydrogenase, propanol-preferring [EC: 1.1.1.1] (inferred from 61% identity to pif:PITG_10292)

Predicted SEED Role

"Alcohol dehydrogenase (EC 1.1.1.1)" in subsystem Fermentations: Mixed acid or Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 1.1.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.1

Use Curated BLAST to search for 1.1.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (359 amino acids)

>mRNA_7070 K13953 adhP alcohol dehydrogenase, propanol-preferring (Rhodosporidium toruloides IFO0880)
MSNPQIPKEGVAVVFDKCNGPIRVDKHHHVVQPSELKPGEVLVRVEYTGVCHTDLHAWKG
DWPAAPKTPLVGGHEGAGHVVAIADGTTTTLKVGDAVGIKWLADSCLNCENCRLGSEATC
DLAQCSGYTVDGSFQQYAVSFARHLTPIPDGLPLEVAAPILCAGVTVWKALKEANAKPGD
WVVISGAGGGLGHLAVQYAAAVGYRVVGIDTGDDKRKLLASYGADTFIDFKQFGGEGKLI
EEVKRVCDGKGPHAAIITSAGGAAYNDALEYLRPHGTLVAVGLPPDTYIKANVFWTVFKS
LRVVGSYVGNRQDAIEALDFAARGKVKPQIVVEPLENLEKVYHRMEQGAVPGRIVLKNF