Protein Info for mRNA_7136 in Rhodosporidium toruloides IFO0880

Name: 15504
Annotation: K01880 GARS, glyS1 glycyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 729 signal peptide" amino acids 1 to 47 (47 residues), see Phobius details TIGR00389: glycine--tRNA ligase" amino acids 89 to 705 (617 residues), 763.2 bits, see alignment E=8.3e-234 PF00587: tRNA-synt_2b" amino acids 293 to 590 (298 residues), 39.6 bits, see alignment E=5.6e-14 PF03129: HGTP_anticodon" amino acids 614 to 705 (92 residues), 74.4 bits, see alignment E=6.5e-25

Best Hits

Swiss-Prot: 61% identical to SYG_SCHPO: Putative glycine--tRNA ligase (grs1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K01880, glycyl-tRNA synthetase [EC: 6.1.1.14] (inferred from 66% identity to cnb:CNBF3810)

Predicted SEED Role

"Glycyl-tRNA synthetase (EC 6.1.1.14) @ Glycyl-tRNA synthetase (EC 6.1.1.14), mitochondrial" (EC 6.1.1.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (729 amino acids)

>mRNA_7136 K01880 GARS, glyS1 glycyl-tRNA synthetase (Rhodosporidium toruloides IFO0880)
MRLREHLYVAGKHNAAHSMNLRSPASTLALALHSLALCMLRGLAQGTRTTLAATPSLTRT
LTSSAALLARSKMSQPTSTAPVKDAHPFERSQLESLLIRRFFYAPAFEIYGGVKGLYDYG
PPGSSLQANIIDTWRKHFIIEEEMLELDTTIMTLSDVLKTSGHVDKFTDWMVKDSKTNEV
YRADHLIEGVLEARLTGDKEARGVKELQEEEDATAKKKKKKVKSVAVKLDDKVVEEYEQI
LAKIDNYTGAELGQLIREHKIVAPETGNEVTEPVEFNLMFDSNIGPTGQLKGYLRPETAQ
GHFVNFNRLLDFNNGRVPFASAQIGRSFRNEISPRSGLLRVREFTMAEIEHFVDPLDKAH
ERFESVKDIKLRLLPKDVQAEGRTDISEMTIGEAVKTGMVDNSTLGYFIARIYLFLTKIG
INPARLRFRQHMANEMAHYAADCWDAEIETSYGWIECVGCADRSAYDLTVHSVKTQNKLV
VRQALKEPRVVERNVPAIDKKAFGPLFKKDAKAIEEAINALSEEELVKAMQQLKEQQQAT
VKVNGQEFQVPANVLTITPTQIKEMVREFVPNVIEPSFGIGRILYSLLEHSFWARADDVN
RGVLSLPPAVAPIKCLIVPLSSNSEFKPLVAQVSQKLRSLGIASRVDDSNASIGKRYARN
DELGTPFGVTLDFASVKNNTMTLRERDTTLQLIGSIDEVIQVVSELCNGSLSWTDAQSRL
QPYSGSQDA