Protein Info for mRNA_7166 in Rhodosporidium toruloides IFO0880

Name: 15534
Annotation: K01626 E2.5.1.54, aroF, aroG, aroH 3-deoxy-7-phosphoheptulonate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 transmembrane" amino acids 111 to 133 (23 residues), see Phobius details PF01474: DAHP_synth_2" amino acids 35 to 491 (457 residues), 605.9 bits, see alignment E=1.8e-186

Best Hits

KEGG orthology group: K01626, 3-deoxy-7-phosphoheptulonate synthase [EC: 2.5.1.54] (inferred from 56% identity to scm:SCHCODRAFT_17831)

Predicted SEED Role

"2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase II (EC 2.5.1.54)" in subsystem Chorismate Synthesis or Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) (EC 2.5.1.54)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.54

Use Curated BLAST to search for 2.5.1.54

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (521 amino acids)

>mRNA_7166 K01626 E2.5.1.54, aroF, aroG, aroH 3-deoxy-7-phosphoheptulonate synthase (Rhodosporidium toruloides IFO0880)
MASPAPAAPQTPWSPQSWRSKPVGQPVAYPDPSSSSSTHPAPDPVLYKKKQGLEDVVHKL
ETLPPIVSATEIERLKLNLANVANGKAFLLQGGDCAELFDYCTSEKIEHRLSLLLSMSLI
LIWGMKMPVVRIARMGGQYAKPRSKQTEVVDGKEIPSFRGHNVNGIDPDDRLPDPERLLS
AYFHSAATVNHVRSLLASGFASLPTGGNHTVPWSLPLAHVRSPELLKSYEDIVKSLSDAL
EFMSVIGVDRGTGGAAGALESADIFMSHEALMLEYESALTRLLPVPAFAASSPGEKGYYC
TSAHTVWIGDRTRALDGAHVEFFRGLRNPVGIKVGPSMEPDELVRLLGIVDPKKEPGKVT
LISRYGADLIDKKLPAHIKAVQQSGHKVIFASDPMHGNTKTSSAYPGVKTRHMHDIVYEI
SASLRIHSELGSRLGGVHLELTGDITEDGLSVTECLGGSMRLEEEQLGLRFESYCDPRLN
FEQSLDIAFMLSQAGGRGRDHQRILDELASRPGSVDSRVKQ