Protein Info for mRNA_7216 in Rhodosporidium toruloides IFO0880

Name: 15584
Annotation: K01535 PMA1, PMA2 H+-transporting ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1054 transmembrane" amino acids 129 to 148 (20 residues), see Phobius details amino acids 154 to 172 (19 residues), see Phobius details amino acids 353 to 373 (21 residues), see Phobius details amino acids 385 to 416 (32 residues), see Phobius details amino acids 748 to 768 (21 residues), see Phobius details amino acids 774 to 794 (21 residues), see Phobius details amino acids 811 to 833 (23 residues), see Phobius details amino acids 853 to 873 (21 residues), see Phobius details amino acids 885 to 906 (22 residues), see Phobius details amino acids 926 to 944 (19 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 92 to 146 (55 residues), 35.5 bits, see alignment 1.3e-12 TIGR01647: plasma-membrane proton-efflux P-type ATPase" amino acids 99 to 899 (801 residues), 812.7 bits, see alignment E=3.1e-248 PF00122: E1-E2_ATPase" amino acids 189 to 419 (231 residues), 119.4 bits, see alignment E=2.8e-38 TIGR01494: HAD ATPase, P-type, family IC" amino acids 283 to 478 (196 residues), 74.8 bits, see alignment E=4.9e-25 amino acids 496 to 637 (142 residues), 64.1 bits, see alignment E=8.4e-22 amino acids 663 to 764 (102 residues), 86.9 bits, see alignment E=1.1e-28 PF00702: Hydrolase" amino acids 436 to 702 (267 residues), 83.6 bits, see alignment E=5e-27

Best Hits

KEGG orthology group: K01535, H+-transporting ATPase [EC: 3.6.3.6] (inferred from 68% identity to cnb:CNBG4400)

Predicted SEED Role

"Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)" (EC 3.6.3.3, EC 3.6.3.4, EC 3.6.3.5)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.6

Use Curated BLAST to search for 3.6.3.3 or 3.6.3.4 or 3.6.3.5 or 3.6.3.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1054 amino acids)

>mRNA_7216 K01535 PMA1, PMA2 H+-transporting ATPase (Rhodosporidium toruloides IFO0880)
MGLRHRKNHKTDDDVESSDTAVNASQEKEPEFQGDEYEKLLAYVDYEAERNKHGGDDDED
EEDGEEKRVWYAPWKKRRVGSAKAKKIPDDWLRTDIGRGLDDAEVEKRRGDFGYNELSSP
SENQILKFISYFRGPILYVMEIAVILAAGLRDWIDFGVIIGILFLNAAVGWYQEKQAGDI
VAELRKGIAMKAVVIRGGNEHEIEARELVPGDIIVIEEGQTIPADARILCSYDDKDSNDV
HSRLDQIERAKKGGSGKKSNDDDDDEDEDKDELKKVRGPSVGSVDQSAITGESLAVDKFI
GETAYYTCGLKRGKVIAVVENSAKQSFVGQTAALVTGSNEVGHFKQVLDGIGTALLVLVV
LFIFGMLIGAFFRNIGIASPKQNNILVYALIFFIVGVPVGLPVVTTTTMAVGAAYLAKQK
AIVQKLTAIESLAGVDILCSDKTGTLTANKLSLNEPYVAEGVKPEWFIAVAVLASSHNIK
SLDPIDKVVVCALKDYPEAKEILKQGWKTNKFSPFDPESKRITAEVEKDGKHYTCAKGAP
NAILRLADFPKEVASHYRSTAASFASRGFRSLGVAIKEEGKEWELLGLLSMSDPPRHDTP
STVREAQELGIQIKMLTGDATAIAKETCKQLGLGANVYDSERLLGGAMSGSEQVDFLEAA
DGFAEVLPRHKYEVVQRLQGRGHLVAMTGDGVNDAPALKVADCGIAVEGASDAARSAADI
VFLDPGLSTIITSIKVAREIFHRMRAYIIYRIALCLHLELFLLLDMLIQNETIRVDLIVF
LAIFADVATIAIAYDNAQSAHRPVEWQLPKVWLMSTVLGLLLAGGTWIARATLFVGRDGK
GGIVQNYGSIQEVLFLEVALTESWLILITRVDIGKDSGKIRWPSFWLISAVFGVDILATG
DAALGWMSGPADRHGGWVDIVSLCRIYGFSVGVTIVIAFVYYVMNKIPWLNNLGRTQKGK
KNVQLENFLTEVQRLAIVHEKSDDPAAPTVFKITRGASDESAPDSGTASNSAKDSKKAEA
KKAEKGKESEEADKQKQEDGKGAEKQNEGVEEKQ