Protein Info for mRNA_7323 in Rhodosporidium toruloides IFO0880
Name: 15691
Annotation: K10579 UBE2M, UBC12 ubiquitin-conjugating enzyme E2 M
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 65% identical to UBC12_YARLI: NEDD8-conjugating enzyme UBC12 (UBC12) from Yarrowia lipolytica (strain CLIB 122 / E 150)
KEGG orthology group: K10579, ubiquitin-conjugating enzyme E2 M [EC: 6.3.2.19] (inferred from 78% identity to scm:SCHCODRAFT_64684)MetaCyc: 60% identical to E2 NEDD8-conjugating enzyme UBE2M (Homo sapiens)
RXN-18741 [EC: 2.3.2.34]
Predicted SEED Role
No annotation
MetaCyc Pathways
- protein NEDDylation (3/3 steps found)
Isozymes
Compare fitness of predicted isozymes for: 6.3.2.19
Use Curated BLAST to search for 2.3.2.34 or 6.3.2.19
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (179 amino acids)
>mRNA_7323 K10579 UBE2M, UBC12 ubiquitin-conjugating enzyme E2 M (Rhodosporidium toruloides IFO0880) MMKIWSLKKSEDQAAKSKPKTSAALIRVQKDLTELDLPPTMKTHFPNPEDLLNFELTITP DEGMYKGGTFKFTFAINNNYPHDAPKVKCVPKIYHPNLDLEGNVCLNILREDWKPVLNLN AVMVGLQYLFLEPNADDPLNKDAANDLRQNRERFMQNVAKSMRGGFVGSEQFDDVRVGR