Protein Info for mRNA_7349 in Rhodosporidium toruloides IFO0880

Name: 15717
Annotation: K07207 TSC2 tuberous sclerosis 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1168 transmembrane" amino acids 618 to 638 (21 residues), see Phobius details PF03542: Tuberin" amino acids 372 to 640 (269 residues), 123.5 bits, see alignment E=1.2e-39 PF02145: Rap_GAP" amino acids 910 to 1126 (217 residues), 157.3 bits, see alignment E=3.5e-50

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1168 amino acids)

>mRNA_7349 K07207 TSC2 tuberous sclerosis 2 (Rhodosporidium toruloides IFO0880)
MRRSVTPVVRSRIMQSVTTIHSHVRYLPGPRRQLVDTVSMPLLETSLEAETDVQVASSMV
ALVTELGRDVLDETEGEGEGPLGMFDKLRLLLIKMAKSSKRTLDRQSTSAPTTPATRRVG
TLAPLSRYGNSGSPAAQRGASSSPAALDIADPPELSSVAVMGLMSIFHVCLEHSTPAASE
NAVIVFRDLLHLFAPGYLSPPDVTPEPAAVPLRTRLLILQWLVRLRADASHRINWMSDVD
ITGPAKLLGRLASTNGDSSPPDAGAPLSPAASEDGHGEARGRSSRQVSMTLPADSAGRSR
SASRLRRQLNEERSPSRTNSLRRAAAAPPVAATPVLWTVPEKLPFDFGSATSAIGGKALS
SFDHNRMRDWTEEEDPGTGQMKVVEAEETLPPSEWLVVLPVSEYLRAVNHILQVEQEWEL
VSYILCHLPEQLSNKHFACGPRCAQQIHVLRKALCDGLRAGDRGDRIFPRTLPVGIKRAE
IHAVAFHCLTALIAYRSLFSKQQQDDIVSTFMLGLGNPRDTAKPCIHALTIAAFELRPSV
TKHLAETVRQLQKIISTAPLGVHILEFIAGVGQEPSLYANFTDADFQTVFGIALKYIQAH
NERLADNPNDVEEGIEYAFSQYVLLLAYYNIAVWYLALRLSERPKFVAFLTRRLVQANEG
KTEVDEATEVCLDMIARYAYSNADPRPRASSFDNLIATPTQAPVPPPKTWLVGNATITVR
KLHAPAWVEVTVRRASGVVRMLWELQNISMTSSAPESDLIAALLRHRETAGLMHGIPSVI
RDALAMLPNPAPPLHVGTRARSASFSGTSASQVPLAQRIEENAVVDAANAAARDVRQVTI
ESGVLTADPSFFTVQLSSFPHVDARMRPLLVPNDPASQRAVTMLDTIPIVDFHKVGVLYA
GQGQTNELDILANTHGSKAYTEFVSGLGTLVRTKGSRDLNIYIGGLDQETDIDGKWTYCW
DDDISQMVFHVATLMPTNRETDPQCTLKKRHIGNDFIKVIWNDSGGEFAFDTLPGDFNFV
NIVIQPHTPAGNPWIGPGMSNNTEFFKVSMQLRPGMPEVGPLGTFKMVTGSSLPHVVRQL
ALHSNIFAQIFLASVGFETGRPAGTSGMTHRIEYSSNWRKRLQQIKLLKKRIAEAQQAAS
PSAENGSSPAQPIDLDQAEAARLFTAWA