Protein Info for mRNA_7376 in Rhodosporidium toruloides IFO0880

Name: 15744
Annotation: K19030 PFKFB4 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01591: 6PF2K
  • amino acids 11 to 228 (218 residues), 214.4 bits, E=1.3e-67
• PF00300: His_Phos_1
  • amino acids 232 to 430 (199 residues), 91.2 bits, E=7.2e-30

Best Hits

KEGG orthology group: K01103, 6-phosphofructo-2-kinase / fructose-2,6-bisphosphatase [EC: 2.7.1.105 3.1.3.46] (inferred from 57% identity to scm:SCHCODRAFT_60710)

Predicted SEED Role

No annotation

MetaCyc Pathways

• fructose 2,6-bisphosphate biosynthesis (2/2 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.105 or 3.1.3.46

Protein Sequence (436 amino acids)

>mRNA_7376 K19030 PFKFB4 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 (Rhodosporidium toruloides IFO0880)
MAAPLYQTDSGRLWHAGQILLVFVGLPARGKTHVSRSVERYLRWLGVRTKVFSLGDHRRR
MLGPSANLPPDYFQPEGRSPETDELRAKVRITLEEEVARYFKENEGQVAIFDANNGTKAA
RIALRQKFEAQGVNVFFIENICDREDIVEANIRSVKISSPDYQGWNPDDAVKDYMGRIAA
HAKRYETMETSGGPFVKIYNIGERLVVNNIRGYLQSRIVFFLMNVHHKKRTIWFARSGQS
LIEHSFKADSDLSPQGVEYAKKLRDFIVAKRKELLEERIKAGEQPHERRLTVWTSARRRC
ISTARPMAELGYKVIQRQQMYELNPGDVDGLSPEQIKEKYPEEFHKAELDPYGHRYPRAE
SYHDLSVRLEPVILELEREPADILFIGHGSVIRCIMAYLQGLTPNEIPKVELRRGDIVQV
TPSAYGVKFVNHFFWQ