Protein Info for mRNA_7412 in Rhodosporidium toruloides IFO0880

Name: 15780
Annotation: K03596 lepA GTP-binding protein LepA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 721 TIGR00231: small GTP-binding protein domain" amino acids 77 to 261 (185 residues), 58.2 bits, see alignment E=8.6e-20 TIGR01393: elongation factor 4" amino acids 77 to 711 (635 residues), 649.3 bits, see alignment E=5.2e-199 PF00009: GTP_EFTU" amino acids 77 to 267 (191 residues), 160.2 bits, see alignment E=7.1e-51 PF00679: EFG_C" amino acids 553 to 601 (49 residues), 27.9 bits, see alignment 3.1e-10 PF06421: LepA_C" amino acids 604 to 711 (108 residues), 137.8 bits, see alignment E=2.3e-44

Best Hits

Predicted SEED Role

"Translation elongation factor LepA" in subsystem Heat shock dnaK gene cluster extended or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (721 amino acids)

>mRNA_7412 K03596 lepA GTP-binding protein LepA (Rhodosporidium toruloides IFO0880)
MLRSGCSGAQKALRTPRTPRRLLLSRTSTPSQPSLWLLESTVYAHVGWSRTLSSTTRCSE
GQAERKLPSLANFPPEKIRNLVNIAHIDHGKSTLADRMLEMTGTIPLKPKNLDMLDGEGK
NEQVLDTLKVEKERGITVRAQSATMFHTHSDGEQYMINLIDTPGHVDFASEMLRSLLPSQ
GAILLVDAAQGVQAQTLTVLDEAMKRNLEIVGTVNKWDLVKDDERGPAAVQELADLLSCE
ESDVLRVSAKTGWGVETVLDAIIERIPPPPSAKEGETLRALAFDSWFDSYRGVVSLISIF
EGELKKGDSITSAMTGKTYTVLDVGILSPREVSIADLPDPDSRVLRKGMVGYITCGMKDP
KDAFLGDTFHLTSHPTPPLESFKPLKSMVFSGIYPLDPGGFLKLEEAIRRLTLTDRSVTV
NRESSSFLGQGFRLGFNGSLHMDVFRQRLEDEFDEEVIVTRPLVPVKIVFKDGTEKTIDN
PADFPDPSSQIKIAEVLEPMIRATIVTPDEYTGAIINLCTSARGLPLSHNYLSTGSVSAA
PVDPNAPVSAALKPRVSLSYLLPLSSIITSFHSSLKSISSGFASFDYEEAPYEPADLVRM
NILVNGTKIDALCTVLHRSELQAEARSWVKRLREAIPRQHYEVVIQAAVGQHIVARESIA
AARKDVTGHLYGGDITRRMKLLSKQKAGKQRLKERSIGNVTIPVKAFHAVLGGQEMKRKS
G