Protein Info for mRNA_7423 in Rhodosporidium toruloides IFO0880

Name: 15791
Annotation: K01568 PDC, pdc pyruvate decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02776: TPP_enzyme_N
  • amino acids 74 to 280 (207 residues), 101.1 bits, E=8.5e-33
• PF00205: TPP_enzyme_M
  • amino acids 325 to 441 (117 residues), 53.6 bits, E=3.1e-18
• PF02775: TPP_enzyme_C
  • amino acids 517 to 603 (87 residues), 54 bits, E=2.5e-18

Predicted SEED Role

"Pyruvate decarboxylase (EC 4.1.1.1); Alpha-keto-acid decarboxylase (EC 4.1.1.-)" (EC 4.1.1.-, EC 4.1.1.1)

MetaCyc Pathways

• pyruvate fermentation to ethanol II (2/2 steps found)
• superpathway of anaerobic sucrose degradation (14/19 steps found)
• acetaldehyde biosynthesis II (1/1 steps found)
• L-methionine degradation III (2/3 steps found)
• pyruvate fermentation to acetate VIII (1/2 steps found)
• butanol and isobutanol biosynthesis (engineered) (5/8 steps found)
• long chain fatty acid ester synthesis (engineered) (2/4 steps found)
• pyruvate fermentation to acetoin III (1/3 steps found)
• superpathway of fermentation (Chlamydomonas reinhardtii) (3/9 steps found)

KEGG Metabolic Maps

• 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
• 1- and 2-Methylnaphthalene degradation
• 3-Chloroacrylic acid degradation
• Ascorbate and aldarate metabolism
• Benzoate degradation via hydroxylation
• Biphenyl degradation
• Fluorene degradation
• Glycolysis / Gluconeogenesis
• Phenylalanine metabolism
• Phenylpropanoid biosynthesis
• Purine metabolism
• Pyruvate metabolism
• Tryptophan metabolism
• Tyrosine metabolism
• Ubiquinone and menaquinone biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.- or 4.1.1.1

Protein Sequence (684 amino acids)

>mRNA_7423 K01568 PDC, pdc pyruvate decarboxylase (Rhodosporidium toruloides IFO0880)
MPVSVTVGLRCDDAAELASSTRSHTLIPASPSLLPLSGSAKHPLEHTHPTSELAQPLNRT
MSSPGQLADDQVYLGTYLLDRLAQLDVKCLFGVPGDFNLTFLDLVEEHPEVQWIGNCNEL
NAAYAADGYARVKQAQINSIREGEQAESKPGQATTHGGKDKTQGGVRGLGALLTTFGVGE
LSAVNGIAGAYSERVPILHIVGVPSTKLQKSKALLHHTLGNGEFTVFEQASAGITCARAF
LQRAEEAAEEIDRVLLAALTTARPAYVTLPTDLVFVPVPKKRLEDPIIPMRVGFEDKNVL
PTGKKVEEEEKNRLQFVVGEIERLWNEAKEPIILIDACAIRYGVGHLVRDLVHATGVKFY
TTPMGRTAIDEDPSNGFGGVYVGEVTDPKVKEVVEKTDLAVMVGSLKSDFNTGEFSYSFP
TEQTVELHSDHTLVQYAHYPSVSFHQLLPALTKVLKHKPNVTHPPSDRGLQTQIPDGDAD
KVVTQAAFWPMMGKFFEEGDIVVAETGTSSFGMISTPLPKGSTFVSQVLWGSIGWTGGAT
LGALLAAKEAPKPRRVILFIGDGSLQLTVQEVATMVRLDLKPILVVLNNDGYTIEKKIHG
ETAGYNDISSWKWQSMLDFFNAYDQPKPTRSWLAPTRADLERILADDEFRKADRIQVLEV
KMDKLDAPVALEKQGKLSAELNAA