Protein Info for mRNA_7480 in Rhodosporidium toruloides IFO0880

Name: 15848
Annotation: K01868 TARS, thrS threonyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 781 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF02824: TGS" amino acids 129 to 188 (60 residues), 47.2 bits, see alignment 3.7e-16 TIGR00418: threonine--tRNA ligase" amino acids 200 to 768 (569 residues), 675.2 bits, see alignment E=5e-207 PF07973: tRNA_SAD" amino acids 298 to 346 (49 residues), 38.5 bits, see alignment 2e-13 PF00587: tRNA-synt_2b" amino acids 448 to 662 (215 residues), 115.9 bits, see alignment E=4.5e-37 PF03129: HGTP_anticodon" amino acids 675 to 767 (93 residues), 74 bits, see alignment E=1.7e-24

Best Hits

Swiss-Prot: 64% identical to SYTC_SCHPO: Threonine--tRNA ligase, cytoplasmic (ths1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K01868, threonyl-tRNA synthetase [EC: 6.1.1.3] (inferred from 68% identity to cci:CC1G_12107)

Predicted SEED Role

"Threonyl-tRNA synthetase (EC 6.1.1.3)" (EC 6.1.1.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (781 amino acids)

>mRNA_7480 K01868 TARS, thrS threonyl-tRNA synthetase (Rhodosporidium toruloides IFO0880)
MLTRTLYPRLLSPVLARPARARISRLSPLPSPAHFSTTCATMSAPHPVHSTAQPSHPENA
VPASGAPTAQPGQEAPKKAPKQKKGDIVGGMAALELNPPPEYLASRVELFDQLKKEYEEK
VASMPREAITITLPDGSTREGKSWETTPMSVALSISKGLADKTVIAKVDGNLWDLERPFE
KSASLELLDFEHPEGKKVWWHSSAHILGECCERHYGCHLAMGPPTDDGFFYEMGMNGDRV
VQQSDYDKLETLAKGVVKDKQKFERLVVSKENLLKMFSYNPFKLHFIKEKVPDGGETTVY
RCGPMIDLCVGPHIPHTGRVKSLAVLKNSSSYFLGDKNNESLQRIYGISFPDTNQMKEYK
KFLEEAAKRDHRKIGKDQELFFFHEMSPGSCFWLPHGTRIYNTLVEFMRSEYRKRNYQEV
ITPNMFNSKLWETSGHWQNYADDMFKLDVEKEQFALKPMNCPSHCLVFGSRDRSYRELPI
RMADFGVLHRNEASGALTGLTRVRRFQQDDAHHFCMPEQIEEEMDVCFQFLNEVYGTFGF
KFELKLSTRPEKFLGKIETWDEAERMLSSALDKFVPGQWVIDEGDGAFYGPKIDITIQDA
LRRKHQCATIQLDFQLPQRFELSYRSAEGGEGGAGEKLVRPVMIHRAILGSVERFTAILT
EHFAGKWPFWLSPRQVVVIPVAGPHKEYAKEVAQKLWDAGIYADADLSDSTLPKKVRNGE
IAQYNFIFVVGSEEMDQRSVNVRNRDDAGNKKARSETIKLDEVMDKLMRLKNERRLDNEL
R