Protein Info for mRNA_7537 in Rhodosporidium toruloides IFO0880

Name: 15905
Annotation: K13524 ABAT 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 507 TIGR00699: 4-aminobutyrate aminotransferase" amino acids 37 to 502 (466 residues), 648.5 bits, see alignment E=2.9e-199 PF00202: Aminotran_3" amino acids 71 to 501 (431 residues), 355.9 bits, see alignment E=1.3e-110

Best Hits

Swiss-Prot: 62% identical to GABAT_USTMA: 4-aminobutyrate aminotransferase (GATA) from Ustilago maydis (strain 521 / FGSC 9021)

KEGG orthology group: K13524, 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC: 2.6.1.19 2.6.1.22] (inferred from 62% identity to uma:UM01080.1)

MetaCyc: 50% identical to 4-aminobutyrate aminotransferase, mitochondrial (Homo sapiens)
2.6.1.ak [EC: 2.6.1.ak]; (S)-3-amino-2-methylpropionate transaminase. [EC: 2.6.1.ak, 2.6.1.22]; 4-aminobutyrate transaminase. [EC: 2.6.1.ak, 2.6.1.22, 2.6.1.19]

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.19

Use Curated BLAST to search for 2.6.1.19 or 2.6.1.22 or 2.6.1.ak

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (507 amino acids)

>mRNA_7537 K13524 ABAT 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase (Rhodosporidium toruloides IFO0880)
MLSVLNRVPRASLAARAATRLFATEHNPPTRFESASVWQNEPSQPKLVTDSVPGPRSAEL
SKEIADFQDPRTHVVVADYAKSRGNYLVDADGNEMLDVFAQIASIAIGYNNPELIALAKT
DEFAIAAMNRPALGSFPSNEWSETIHKGLLSVAPKGTPHLFTQMCGSCANEGALKAAFMA
YRARQRGEQGIKDFTSEEMSSCMKNASPGSPDLVAMSFKSAFHGRLFGSLSLTRSKAIHK
LDIPAFDWPAISWPTMKYPLEEYASENAEAEARTIALVEETIIAQKKKGKDVAALIVEPI
QSEGGDNHASPSFFKALRTVTREHGVFMIVDEVQTGVGATGAFWAHDKWKLDHPPDFVTF
SKKMQAAGFYHAEGTRASLPYRNYNTWMGDPMRALQAREMIGFIKAHGLVAHTAAIGDEL
YSSLTDLSKRYSGQIHNLRGKDCGTFIAWDAASAEQRDKFVGEMRKVGVVMGGCGDNAVR
LRPMLVFGDKQKDVLLEKMEGVFKNMS