Protein Info for mRNA_7537 in Rhodosporidium toruloides IFO0880
Name: 15905
Annotation: K13524 ABAT 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 62% identical to GABAT_USTMA: 4-aminobutyrate aminotransferase (GATA) from Ustilago maydis (strain 521 / FGSC 9021)
KEGG orthology group: K13524, 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC: 2.6.1.19 2.6.1.22] (inferred from 62% identity to uma:UM01080.1)MetaCyc: 50% identical to 4-aminobutyrate aminotransferase, mitochondrial (Homo sapiens)
2.6.1.ak [EC: 2.6.1.ak]; (S)-3-amino-2-methylpropionate transaminase. [EC: 2.6.1.ak, 2.6.1.22]; 4-aminobutyrate transaminase. [EC: 2.6.1.ak, 2.6.1.22, 2.6.1.19]
Predicted SEED Role
No annotation
MetaCyc Pathways
- β-alanine degradation I (2/2 steps found)
- 4-aminobutanoate degradation I (2/2 steps found)
- 4-aminobutanoate degradation III (2/2 steps found)
- L-valine degradation I (6/8 steps found)
- GABA shunt (3/4 steps found)
- superpathway of 4-aminobutanoate degradation (2/3 steps found)
- β-alanine degradation III (1/2 steps found)
- 4-aminobutanoate degradation II (1/2 steps found)
- superpathway of L-arginine and L-ornithine degradation (7/13 steps found)
- superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (5/11 steps found)
- 4-aminobutanoate degradation V (2/7 steps found)
- nicotine degradation I (pyridine pathway) (4/17 steps found)
KEGG Metabolic Maps
- Alanine and aspartate metabolism
- Butanoate metabolism
- Glutamate metabolism
- Propanoate metabolism
- Valine, leucine and isoleucine degradation
- beta-Alanine metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.19
Use Curated BLAST to search for 2.6.1.19 or 2.6.1.22 or 2.6.1.ak
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (507 amino acids)
>mRNA_7537 K13524 ABAT 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase (Rhodosporidium toruloides IFO0880) MLSVLNRVPRASLAARAATRLFATEHNPPTRFESASVWQNEPSQPKLVTDSVPGPRSAEL SKEIADFQDPRTHVVVADYAKSRGNYLVDADGNEMLDVFAQIASIAIGYNNPELIALAKT DEFAIAAMNRPALGSFPSNEWSETIHKGLLSVAPKGTPHLFTQMCGSCANEGALKAAFMA YRARQRGEQGIKDFTSEEMSSCMKNASPGSPDLVAMSFKSAFHGRLFGSLSLTRSKAIHK LDIPAFDWPAISWPTMKYPLEEYASENAEAEARTIALVEETIIAQKKKGKDVAALIVEPI QSEGGDNHASPSFFKALRTVTREHGVFMIVDEVQTGVGATGAFWAHDKWKLDHPPDFVTF SKKMQAAGFYHAEGTRASLPYRNYNTWMGDPMRALQAREMIGFIKAHGLVAHTAAIGDEL YSSLTDLSKRYSGQIHNLRGKDCGTFIAWDAASAEQRDKFVGEMRKVGVVMGGCGDNAVR LRPMLVFGDKQKDVLLEKMEGVFKNMS