Protein Info for mRNA_7657 in Rhodosporidium toruloides IFO0880

Name: 16025
Annotation: KOG2743 Cobalamin synthesis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 PF02492: cobW" amino acids 33 to 220 (188 residues), 164.7 bits, see alignment E=2.5e-52 PF01926: MMR_HSR1" amino acids 36 to 207 (172 residues), 24.4 bits, see alignment E=4.1e-09 PF07683: CobW_C" amino acids 337 to 402 (66 residues), 27.5 bits, see alignment E=3.6e-10

Best Hits

Predicted SEED Role

"Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (428 amino acids)

>mRNA_7657 KOG2743 Cobalamin synthesis protein (Rhodosporidium toruloides IFO0880)
MSTEDLRVEDLSVSDDLEMDEVPQLVEPLAKVPLTVLTGYLGAGKSTLLDYILKEQHGRR
IAVIMNEFGDTTDIESKAISVQSDEAMVEEWLELNNGCLCCSVRDTGLLAIINLMEKKGR
FDQIMLETTGLADPAPIIESFWNEPALNLEVGLDAVVAVVDAAGIEKQLQEPRPDGSYNE
AQRQVATADVILLNKVDLVQPEDLDRIEAALRSINSTALIHRTTRSSIDLSLILDLNIYA
SPSIPIRPETLAPFVQPDDKAAQCAGCQSGDSSHSHTHSTSSSSAHANDISSLTIPLPVL
PSVENGSAFYRVVSRLIWDSKLPSTSTSSSDEPLSLDLLRTKGFLRTQDGQSYILQGVRD
IFDISPVPPATVAAEEREVKPKLVLIGRGIKGREGEIARRFEEGLRMALEEDEREGGADG
EGDKDMAE