Protein Info for mRNA_7774 in Rhodosporidium toruloides IFO0880

Name: 16142
Annotation: KOG1546 Metacaspase involved in regulation of apoptosis

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 PF00656: Peptidase_C14" amino acids 168 to 455 (288 residues), 201.8 bits, see alignment E=9.3e-64

Best Hits

Swiss-Prot: 51% identical to MCA1A_NEUCR: Metacaspase-1A (casA) from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)

KEGG orthology group: None (inferred from 51% identity to ncr:NCU09882)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (462 amino acids)

>mRNA_7774 KOG1546 Metacaspase involved in regulation of apoptosis (Rhodosporidium toruloides IFO0880)
MSYPGANYHAHKQQHYQQNQGYAPPPGPPQGYGYGGDGYGGGGYGGGPGGYAPPPGPPPG
QYGGGGYGGYQGQGGYNTGYTSPPPSDYNQGMPHPHHEQYQYNAPPEFGGQNSYAQQYDP
PPGPPPMHYGAQEQQYNVPSQYQGGQFAMHSGPTGDQSQYYSNLSGRRKALCIGINYTGT
RSQLNGCHNDARNMAKFLCERYNYKEEDIVMLLDTPDATQMSLPTRANIIRGMQWLVKDA
RPNDALFFHYSGHGGQQAAVEADEEDGYDENIYPLDHEVAGTIVDNDMHRLLVTPLPQGC
RLTAIFDCCHSGSALDLPYMYSTKGVLKEPNMLADAGSGALGAATSYMRGDLGGVFKSVM
GVGKRIMNGDKASEYTKQTRSSNADVISWSGCKDTQTSADTSIQGQSTGAMSYSFITALT
KYPQQNYLQLLNTIRDELQGKYSQKPQLACSHPLDLNLLFVC