Protein Info for mRNA_7863 in Rhodosporidium toruloides IFO0880

Name: 16231
Annotation: K11407 HDAC6 histone deacetylase 6

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 881 PF00850: Hist_deacetyl" amino acids 205 to 515 (311 residues), 282.9 bits, see alignment E=4e-88 PF09757: Arb2" amino acids 571 to 824 (254 residues), 133.9 bits, see alignment E=5.7e-43

Best Hits

Predicted SEED Role

"Deacetylases, including yeast histone deacetylase and acetoin utilization protein" in subsystem Hydantoin metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (881 amino acids)

>mRNA_7863 K11407 HDAC6 histone deacetylase 6 (Rhodosporidium toruloides IFO0880)
MDGFSQPVYTQAIPADASQQSAPATQLEQPVASTSTAPATIAPVSAAAASAQVEPQPVDP
PISENSAPLQPGQPRLFPFPEQDPNALPLTGFASVPARAAVLPNAQPYTRPPPYDRPNVE
LGKGLSRDPPPRRFVSEADIKASHTNGHGDLLRQPGVVREEEIATLTVDQLRKMGLGRAP
SGFCYSARMTLHAPLPKTVDSNDPHPEQPARITGIFNKLLNGGLTSRMVRVQVREALREE
VMLVHSEGHWERVRATGFQTIEYLETCKEFFERLSLYVNPDSAFCARLSCGGVIEMARAV
AEGQIRNGFAIVRPPGHHAEPEEAMGFCFFNNAAVAAKWLRTVYGSGTQKDVNGKEIKMN
RILILDWDVHHGNGTQRAFEDDDDILYISLHRHGNGFYPGGDYGALESVGSGKGRGFSVN
IPFMNEGMGDADYLYAFQNIVMPIAYEYAPDLVIVSAGYDAAKGDELGKMNVSPDGYAHM
THMLSALAGGKLLLALEGGYNVNAIAESAYACVKVIVGDELPVMSSIGAASLAATNTVHD
VRRMQAQYWKCMGEAVLSQEELSKAGKIESLSEVLKKHRLYELWHEYGLFDVEFNSPTLE
EAYSNQLLVSENVYDADVLLLFMHDLGSMKAAYTAATLDSDLERTQLLDTSREVLDWAME
DHDFGVIDVNLLAHLATVKGQPIDAKRDKAREKELALYVWDQIVQMSSAQHVILFGSGAG
CNALMDIVRNRFGLVQQRVRACVSVLGHEHPPELEASTGARNWYKNHSLVLLPSTHPLQE
DARRAGKHQKKFGNVYRATAEDESRPTHLLRASMPKIKEFIAERVPITIAPAAATSSSSG
GDIEMATRMASVEPTGAPAPAAPAAEANGSSFAPPAPAPAA