Protein Info for mRNA_7956 in Rhodosporidium toruloides IFO0880

Name: 16324
Annotation: K03146 THI4, THI1 thiamine thiazole synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 transmembrane" amino acids 114 to 128 (15 residues), see Phobius details TIGR00292: thiazole biosynthesis enzyme" amino acids 93 to 354 (262 residues), 252.2 bits, see alignment E=2.3e-79 PF01946: Thi4" amino acids 95 to 338 (244 residues), 312.1 bits, see alignment E=5.9e-97 PF01266: DAO" amino acids 113 to 152 (40 residues), 28.6 bits, see alignment 3.4e-10 PF00890: FAD_binding_2" amino acids 113 to 150 (38 residues), 22.9 bits, see alignment 1.3e-08 PF13450: NAD_binding_8" amino acids 116 to 152 (37 residues), 28.9 bits, see alignment 3.4e-10

Best Hits

Predicted SEED Role

"Thiazole biosynthetic enzyme Thi4" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (383 amino acids)

>mRNA_7956 K03146 THI4, THI1 thiamine thiazole synthase (Rhodosporidium toruloides IFO0880)
MSNYNGFKSSIASLRVAGAHAPPSKNADDLKAAVASTELPASPPDSDASSDVDSARKVGG
DGATWAGLKEEKTESWTVDWDGSFKFAPIKEHIVSRAMSSRYGKDQYETAISDIVIVGAG
SAGLSAAYAIAKERPDLKVTIIEAAVAPGGGAWVGGQLQSAMVVRKPGHFFLDELNVPYE
DEGDYVVVKHAGIFTASCLAAVLKFPNVKLYNATAVEDLISRPDPLSKVPDARRIAGVVV
NYTLVTLAHGLQSCMDPQTITAPVVMSFAGHDGPFGAFSVKRLVSTGLVESLGDMRTLDM
RQAEDFIVNNTREVVPGLVTGGMELAELDGSSRMGASFAAMMVSGIKAAKIAIKMYDSYE
IEDGEVVGWAGVGKKLAAAKISA