Protein Info for mRNA_7991 in Rhodosporidium toruloides IFO0880

Name: 16359
Annotation: K02132 ATPeF1A, ATP5A1, ATP1 F-type H+-transporting ATPase subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 535 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR00962: ATP synthase F1, alpha subunit" amino acids 31 to 533 (503 residues), 770.2 bits, see alignment E=4.6e-236 PF02874: ATP-synt_ab_N" amino acids 51 to 118 (68 residues), 63.5 bits, see alignment E=3.3e-21 PF00006: ATP-synt_ab" amino acids 175 to 398 (224 residues), 239.2 bits, see alignment E=5.9e-75 PF00306: ATP-synt_ab_C" amino acids 405 to 527 (123 residues), 137.5 bits, see alignment E=4.7e-44

Best Hits

Swiss-Prot: 75% identical to ATPA_NEUCR: ATP synthase subunit alpha, mitochondrial (atp-1) from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)

KEGG orthology group: K02132, F-type H+-transporting ATPase subunit alpha [EC: 3.6.3.14] (inferred from 80% identity to lbc:LACBIDRAFT_305432)

MetaCyc: 73% identical to ATP synthase subunit alpha, mitochondrial (Homo sapiens)

Predicted SEED Role

"ATP synthase alpha chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (535 amino acids)

>mRNA_7991 K02132 ATPeF1A, ATP5A1, ATP1 F-type H+-transporting ATPase subunit alpha (Rhodosporidium toruloides IFO0880)
MHRSLRLASIASKAAARPALARAYATAKPAASEVASILESRISGSTAGADVQETGRVLTI
GDGIARVYGLRNVQAEEMVEFASGVRGMCLNLEADNVGVTIFGNDRAIREGDTVKRTGNI
VDIPVGPDMLGRVVDALGNPIDGKGPIKAAERRRAQVKAPGVLPRTSVKEPMLTGLKSVD
AMVPIGRGQRELIIGDRQTGKTAVAIDTILNQKRWNDGNDDKKKLYCIYVAVGQKRSTVA
QLVQTLEENDALKYSVIVAATASEAAPLQYLAPFAGTAIGEWFRDNGKHALIIYDDLSKQ
AVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSAKLSDKHGGGSLTALPVIETQGGDV
SAYIPTNVISITDGQIFLEAELFFKGVRPAINVGLSVSRVGSSAQTKVMKAVAGSLKLYL
AQYRDVAAFAQFGSDLDASTRFLLNRGSRLTELLKQGQYQPLPIEIQVPIIYAGVNGLLD
RVPVDKIGAWEASFKDHLKGQQSLLEKVSAGKMTPELDAEIKKTVQEHVSQFVSA