Protein Info for mRNA_8075 in Rhodosporidium toruloides IFO0880

Name: 16443
Annotation: K13525 VCP, CDC48 transitional endoplasmic reticulum ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 823 PF02359: CDC48_N" amino acids 27 to 107 (81 residues), 66.8 bits, see alignment E=1.9e-21 TIGR01243: AAA family ATPase, CDC48 subfamily" amino acids 38 to 783 (746 residues), 836 bits, see alignment E=4.3e-255 PF02933: CDC48_2" amino acids 128 to 192 (65 residues), 36.6 bits, see alignment 3.7e-12 PF00004: AAA" amino acids 243 to 372 (130 residues), 159.4 bits, see alignment E=8.2e-50 amino acids 516 to 650 (135 residues), 154.6 bits, see alignment E=2.4e-48 PF05496: RuvB_N" amino acids 243 to 317 (75 residues), 25.8 bits, see alignment E=9.9e-09 amino acids 515 to 549 (35 residues), 22.6 bits, see alignment (E = 9.3e-08) PF07728: AAA_5" amino acids 243 to 361 (119 residues), 22.7 bits, see alignment E=1e-07 PF07724: AAA_2" amino acids 243 to 340 (98 residues), 32.3 bits, see alignment E=1.3e-10 PF17862: AAA_lid_3" amino acids 395 to 435 (41 residues), 49.7 bits, see alignment 3e-16 amino acids 672 to 712 (41 residues), 41.4 bits, see alignment 1.2e-13 PF09336: Vps4_C" amino acids 746 to 779 (34 residues), 22.7 bits, see alignment (E = 9.7e-08)

Best Hits

Swiss-Prot: 72% identical to CDC48_SOYBN: Cell division cycle protein 48 homolog (CDC48) from Glycine max

KEGG orthology group: None (inferred from 74% identity to cal:CaO19.9876)

Predicted SEED Role

"Cell division protein FtsH (EC 3.4.24.-)" in subsystem Bacterial Cell Division (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (823 amino acids)

>mRNA_8075 K13525 VCP, CDC48 transitional endoplasmic reticulum ATPase (Rhodosporidium toruloides IFO0880)
MANDPSKEQKVDDSATAILRPKKSPNRLIVDESTSDDNSVAQLNPATMETLQLFRGDTII
VRGKKRKDTVLIILSSEDVDEGKIQLNKVARNNLRVKLGDLCTVHACHDIKYGKRIHVLP
FDDSIEGLSGDIFNVFLKPYFLEAYRPVRKGDIFLAKGASRSVEFKVVETDPAEYCIVAQ
DTVIHTEGEPIKREDEENNLSEVGYDDIGGCRKQLAQIRELVELPLRHPQLFKSIGIKPP
RGILMYGPPGTGKTLMARAVANETGAFFFLINGPEIMSKMAGESESNLRKAFEEAEKNAP
AIIFIDEIDSIAPKREKTNGEVERRVVSQLLTLMDGMKARSNIVVMAATNRPNSIDPALR
RFGRFDREVDIGIPDATGRLETLRIHTKNMKLADDVDLEKIAADTHGYVGADIASLCSEA
AMQQIREKMDLIDLEEDTIDAEVLDSLGVTMDNFRFALGTSNPSALRETVVEIPTVTWDD
IGGLDKVKIELQETVQYPVEHPEKFLKYGMSPSKGVLFYGPPGTGKTLLAKAIAHECQAN
FISIKGPELLTMWFGESEANVRDVFDKARAAAPVVMFFDELDSIAKARGGGPGGDAGGAG
DRVLNQILTEMDGMNAKKNVFVIGATNRPDQIDPALLRPGRLDQLIYIPLPDEPSRTSIL
KAALKRSPIAADVDLGFIAKNTHGFSGADLTEVCQRAAKLAIRASIEADMQKDRERKAKI
EELGEEAVVKQEEEQMDADDEAGEDPVPYITREHFEEAMRFARRSVSDQDIRRYELFAQN
LQQSRSFGSSFKFPEGGAAGEAGAGATGGAAFGAEQEEDDLYS