Protein Info for mRNA_8107 in Rhodosporidium toruloides IFO0880
Name: 16475
Annotation: K01937 pyrG, CTPS CTP synthase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 68% identical to PYRG_SCHPO: CTP synthase (ura7) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)
KEGG orthology group: K01937, CTP synthase [EC: 6.3.4.2] (inferred from 70% identity to cnb:CNBC7010)MetaCyc: 61% identical to CTP synthase 1 (Homo sapiens)
CTP synthase. [EC: 6.3.4.2]
Predicted SEED Role
"CTP synthase (EC 6.3.4.2)" (EC 6.3.4.2)
MetaCyc Pathways
- superpathway of histidine, purine, and pyrimidine biosynthesis (38/46 steps found)
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (15/18 steps found)
- superpathway of L-citrulline metabolism (10/12 steps found)
- L-citrulline biosynthesis (7/8 steps found)
- L-asparagine biosynthesis III (tRNA-dependent) (4/4 steps found)
- glutaminyl-tRNAgln biosynthesis via transamidation (4/4 steps found)
- ammonia assimilation cycle III (3/3 steps found)
- L-glutamate biosynthesis I (2/2 steps found)
- superpathway of pyrimidine ribonucleotides de novo biosynthesis (7/9 steps found)
- L-glutamine degradation I (1/1 steps found)
- superpathway of pyrimidine nucleobases salvage (3/4 steps found)
- UTP and CTP de novo biosynthesis (2/3 steps found)
- superpathway of pyrimidine ribonucleosides salvage (7/10 steps found)
- UTP and CTP dephosphorylation II (1/3 steps found)
- L-glutamate and L-glutamine biosynthesis (3/6 steps found)
- UTP and CTP dephosphorylation I (3/7 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 6.3.4.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (600 amino acids)
>mRNA_8107 K01937 pyrG, CTPS CTP synthase (Rhodosporidium toruloides IFO0880) MKYILVSGGVISGIGKGVIASSTGLLLKTLGFNVTAIKIDPYMNIDAGTMSPTEHGEVFV LDDGGEADLDLGNYERYLNVTLGRDNNITTGKIYREVIEKERKGDYLGKTVQVIPHVTDA IQDWVERVAQIPVDESDQAPDVCIIELGGTVGDIESAPFVEAMRQFQFRVGKDNFALLHV SLVPSINGELKTKPTQASIRDLRGLGLMPDLIACRCPAPLPLSVVSKISMFCHVANEQVV AVHDVSSLYHVPLLLKDQGLVKFLQHRLKLDQIRLPEPRVARGTKLLTMWKDLTISYDRL FDKVSICLVGKYTSLQDSYTSVIKSLEHAAMKCGRKLQITWVESSDLEKEAQQERPKEFH AAWQAVCTANGILVPGGFGLRGTEGMIAAAKWAREKKIPYLGICLGFQIAVIEFARGVLG LKDAHSAELMETTPDPVIIFMPEISKTHLGGTMRLGLRPTVFQPNTEWSQVRKLYGDADV IWERHRHRYEVNPAYVEQIEKAGFLFTGRDERGERMQVAELKDHPYFVGLQAHPEFCTRP LNPSPAFLGFIASAAGCLDEQIAGQASYEPPHPKSHLHMENREVPQIELVTEQVAKVTVA