Protein Info for mRNA_8196 in Rhodosporidium toruloides IFO0880

Name: 16564
Annotation: K13501 TRP1 anthranilate synthase / indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00566: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase
  • amino acids 2 to 164 (163 residues), 157.3 bits, E=1.9e-50
• PF00117: GATase
  • amino acids 17 to 163 (147 residues), 120.8 bits, E=1.6e-38
• PF07722: Peptidase_C26
  • amino acids 48 to 148 (101 residues), 29.6 bits, E=1.5e-10
• PF00218: IGPS
  • amino acids 204 to 484 (281 residues), 283.8 bits, E=2.6e-88
• PF00697: PRAI
  • amino acids 596 to 775 (180 residues), 138.4 bits, E=6.6e-44

Predicted SEED Role

"Phosphoribosylanthranilate isomerase (EC 5.3.1.24)" in subsystem Auxin biosynthesis or Tryptophan synthesis (EC 5.3.1.24)

MetaCyc Pathways

• superpathway of aromatic amino acid biosynthesis (16/18 steps found)
• superpathway of L-tryptophan biosynthesis (12/13 steps found)
• L-tryptophan biosynthesis (5/6 steps found)
• superpathway of chorismate metabolism (28/59 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of phenylpropanoids
• Biosynthesis of plant hormones
• Phenylalanine, tyrosine and tryptophan biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.24

Protein Sequence (781 amino acids)

>mRNA_8196 K13501 TRP1 anthranilate synthase / indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (Rhodosporidium toruloides IFO0880)
MTVIRSDALTLDELRAQHPTMTHLVISPGPGHPLKDSGISVDAIDYYAGKIPILGVCMGL
QAITVKYGGVVEQAGEYVHGKTSAILHDGKGLFKGLAQGVAGTRYHSLAARINSLPEELV
VTSRTEGGIIMGLRHKEFSIEAVQYHPESILSEEGKLMLANFLSWKGGRWSELPEVLEPV
KGFSASAPLANGAAPSPSAVPTILQKIEQQRILDVAKAKATPGYKPSDLESLIALHVPPP
LISFHQRLRPSATSTSATSAVPHMALLAEVKRASPSKGDIVDASSPSAPAIALSYALAGA
SVISVLTEPKWFKGSLDDMRAVRAAVDALPNRPAILRKDFILDPYQIDEARVYGADTVLL
IVAMLDDAKLASLYGHSVARGMEPLVEVNNAEELERALKVGAKVIGVNNRNLHDFNVDMS
TTSRIADVIKEKYPERAGEVILIALSGITGRKDVERYQAQGVSAVLVGESLMRANDKGAF
VKELLGLSTSVAPSSLVNGAAQVVQAAASAVVGAVTGNSTSLSHKAPLVKICGLKTPEAA
LTTADAGADLLGLIFVPGSKRNVSLTQAGEIISAVRAHHAGPKQAEAAAAALDTSDWFSL
QASRISAHPRKPLFVGVFQNPSLETVLSTVDALGLDLVQLHGSEPTHWARLIPVPVIRAF
HVDEKAEADAEEAAQLREATRPGFHALPLLDTKVSKDKGALSGGAGRVFDWAVASRLVSS
RVQEGHRDLPIVLAGGLDAANVKEGVQTVRPFAVDVSGGVETNGEKDLDKIREFIRLAKE
A