Protein Info for mRNA_8223 in Rhodosporidium toruloides IFO0880
Name: 16591
Annotation: K00801 FDFT1 farnesyl-diphosphate farnesyltransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Squalene synthase (EC 2.5.1.21)" (EC 2.5.1.21)
MetaCyc Pathways
- epoxysqualene biosynthesis (2/3 steps found)
- superpathway of ergosterol biosynthesis I (16/26 steps found)
- 4,4'-diapolycopenedioate biosynthesis (1/9 steps found)
- botryococcenes and methylated squalene biosynthesis (1/9 steps found)
- staphyloxanthin biosynthesis (1/9 steps found)
- cholesterol biosynthesis I (5/16 steps found)
- cholesterol biosynthesis III (via desmosterol) (5/16 steps found)
- hopanoid biosynthesis (bacteria) (3/14 steps found)
- cholesterol biosynthesis II (via 24,25-dihydrolanosterol) (3/16 steps found)
- superpathway of cholesterol biosynthesis (14/38 steps found)
- superpathway of ergosterol biosynthesis II (5/26 steps found)
KEGG Metabolic Maps
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of plant hormones
- Biosynthesis of steroids
- Biosynthesis of terpenoids and steroids
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.5.1.21
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (419 amino acids)
>mRNA_8223 K00801 FDFT1 farnesyl-diphosphate farnesyltransferase (Rhodosporidium toruloides IFO0880) SKVASLLLYAITRPSEVKAIITYKLWRDPLNTIERNPESGWDRPEMKRCWEFLDLTSRSF AAVIHELDGDLSRVVALFYLVLRGLDTIEDDMTIPIEKKAPLLEEFYQKLEVDGWNFQES GPNEKDRILLQEFQVVVAEFKRLDQHYRTAISDITKKMGAGMSRYAKLHAASGGKFSVDT LPSFDLYCHYVAGLVGEGLSRLFSASQKESPYLGEQLTLSNSMGLMLQKTNILRDFREDV DEGRVFWPAEIWKKYVSAPEELYKKGNEEKALWALSEMTVDALAHATDALDYLTLLRNQS VFNFCAIPQVMAIATLERCFMNPAVVQRNVKIRKGEAVTLILGATNPRDVSYMFRDYARK IHAKARPNDPSFIKIAVLVGRIEQWTETRYPSFISPSMPVPTSSEDWAPGRDARIKQLP