Protein Info for mRNA_8290 in Rhodosporidium toruloides IFO0880

Name: 16658
Annotation: K02327 POLD1 DNA polymerase delta subunit 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1118 PF03104: DNA_pol_B_exo1" amino acids 153 to 492 (340 residues), 294.7 bits, see alignment E=1.4e-91 TIGR00592: DNA polymerase (pol2)" amino acids 260 to 985 (726 residues), 331.1 bits, see alignment E=9e-103 PF00136: DNA_pol_B" amino acids 556 to 987 (432 residues), 505 bits, see alignment E=2.9e-155 PF14260: zf-C4pol" amino acids 1024 to 1097 (74 residues), 64.5 bits, see alignment 1.5e-21

Best Hits

Swiss-Prot: 68% identical to DPOD_SCHPO: DNA polymerase delta catalytic subunit (pol3) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K02327, DNA polymerase delta subunit 1 [EC: 2.7.7.7] (inferred from 63% identity to act:ACLA_075510)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1118 amino acids)

>mRNA_8290 K02327 POLD1 DNA polymerase delta subunit 1 (Rhodosporidium toruloides IFO0880)
MDGEPVTKRRRTTPPVSQGEPATVAGEPTADANLATQQDIPDEDHAAPPSSAAGAHAKPL
SALFQAKTPSPKKSKRTVDLRQAGRIGEEDKENFTALLARLNKETPQEEAEKWGRPDAPK
LNPQRDGLIFQQIDIEEFSAGGGAPTIRAFGVTKNGNSVLLHVKGFLPYFWVSAPRGFTN
SDCLPFMEHLNAAHFNGVRPVKAVSLANKRSLWGYKGDAVSPFIKITVMDTKQYPKVRNA
FERGEVQYKGFFDGTALMTYESNIAYTLRFMIDHHIVGMNWLELKPGTYERAKNPVSNCQ
YEIECQHDQLISHPAEGEWSGIAPLRILSFDIECAGRKGIFPEPEIDPVIQIANMVTRQG
ESKPFIRNVFTLNTCAHIVGSDVLEFKKEADLLSKWRKFVEEVDPDLIIGYNTSQFDFPY
LMDRAKALKVSDFPYFSRLKGVKTEVKDTHFSSKAYGTRDSKETSMDGRLQLDILQVMQR
DYKLRSYTLNSVCAHFLGEQKEDVHHSVITDLQNGTAESRRRLAVYCLKDAYLPQRLMDK
LMCFINYTEMARVTGIPFNYLLSRGQQIKVISQLYRQALKTGYVIPALKQEGSDEQYEGA
TVLEPEQGYYDVPIATLDFASLYPSIMQAHNLCYTTLLDVKIAQALNLKEGEDFVRTPNG
DLFVKAHKRKGLLPTILEDLLAARKRARAELKQEKDPFKRAVLDGRQLALKVSANSVYGF
TGATIGKLPCLPISMSVTAYGREMIDQTKEVVQSTYNTANGYDYDAKVIYGDTDSVMVRF
GCPDLETAMKLGAEAAEFVTSKFIKPIKLEFEKVYYPYLLISKKRYAGLYWTKPEKYDKM
DTKGIETVRRDNCRLVVTVIDTCLRKMLIERDVRGAEDYAKQVISDLLQNKVDLSQLVIT
KALAKADYAAKQAHVELAERMKKRDAGSAPAMGDRVAYVIIKGTKDARAYEKSEDPLYVL
ENNIPIDTKYYLDNQLSKPLMRIFEPILGEKASSLLAGDHTRTVSIVAPTVGGLMKFAVK
TVTCLGCRTPLKPNSLNQAVCNNCRPRTAELHAKQVSIAAQAETAYARLWTQCQRCQGSL
HQDVLCTSKDCPIFYMRKKAQKEAADAVGTLKRFDGEW