Protein Info for mRNA_42 in Rhodosporidium toruloides IFO0880

Name: 8410
Annotation: K09494 CCT2 T-complex protein 1 subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 TIGR02341: T-complex protein 1, beta subunit" amino acids 4 to 522 (519 residues), 926.8 bits, see alignment E=1.7e-283 PF00118: Cpn60_TCP1" amino acids 30 to 517 (488 residues), 489.3 bits, see alignment E=6.3e-151

Best Hits

Swiss-Prot: 69% identical to TCPB_YEAST: T-complex protein 1 subunit beta (CCT2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

KEGG orthology group: K09494, T-complex protein 1 subunit beta (inferred from 82% identity to cne:CNA04280)

Predicted SEED Role

"Heat shock protein 60 family chaperone GroEL / Thermosome subunit" in subsystem GroEL GroES or Staphylococcal pathogenicity islands SaPI or Thermosome, archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (525 amino acids)

>mRNA_42 K09494 CCT2 T-complex protein 1 subunit beta (Rhodosporidium toruloides IFO0880)
MAANILNAEATQERAENARLSSFVGALALGDLVKSTLGPKGMNKILHSASTGEITVTNDG
ATILKSIALDNPAAKILVNISKVQDDEVGDGTTSVTVLASEILREAEKLVTIQRVHPQTV
VEGFRIASKAALQALENAAEDHGKDEAQFREDLLAIARTTLSSKVLAADKNYFAKLAVDA
VMRLKGSTDLDHIQIIKKQGGKLTDSYLDEGFILDKKIGVNCPHRMENAKILIANTPMDT
DKIKIFGARVKVDSTGKLAELERAEREKMKAKVAKIKASGVTCFVNRQLIYNYPESLFAE
AGIMSIEHADFEGVERLALVTGGEIASTFEDPQAVKLGQCDVIEEIMIGEDKLIKFSGVA
AGEACTVVLRGATGQMIEEADRSLHDALSVLSQTVKETRVVLGGGCAEMTMAVAVDEEAK
RTEGKKALAVEAFARALRQIPTILADNAGYDSSDLVAKLRAAHYEGRTDAGLDMEKGTVG
SMKECGVTESYKLKRQVILSASEAAEMILRVDDILRSAPRKREGH