Protein Info for mRNA_68 in Rhodosporidium toruloides IFO0880

Name: 8436
Annotation: K12599 SKI2, SKIV2L antiviral helicase SKI2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1271 transmembrane" amino acids 949 to 966 (18 residues), see Phobius details PF17911: Ski2_N" amino acids 54 to 190 (137 residues), 125.7 bits, see alignment E=2.9e-40 PF00270: DEAD" amino acids 299 to 447 (149 residues), 63.6 bits, see alignment E=5.3e-21 PF04851: ResIII" amino acids 310 to 445 (136 residues), 22.9 bits, see alignment E=2e-08 PF13234: rRNA_proc-arch" amino acids 790 to 1061 (272 residues), 97.1 bits, see alignment E=4.4e-31 PF08148: DSHCT" amino acids 1088 to 1259 (172 residues), 168 bits, see alignment E=3.7e-53

Best Hits

Predicted SEED Role

"FIG005666: putative helicase" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1271 amino acids)

>mRNA_68 K12599 SKI2, SKIV2L antiviral helicase SKI2 (Rhodosporidium toruloides IFO0880)
MRGRQTDEQRAELLRELGVGQTPSPEQVRADIEQEWLLSSKDGRKELAAAEWAMHWNRDP
DLRSLLHIEPTQPTTSLEFISSGLSGEITGYREVTNTASARLATNSTSLDRKPASYEGSF
VRGKSSYFPFRPGGLGDIVTHEDEGAEGEGGLEKAAEGLEKAFQKGQGGIRTIPPGFTRG
LDFGPLADDPTSNLIEEEEEEVEVKPIYRPMLELQNEGRAKAVTNGRPTEQAPVLDSAIE
ELLPTRRLVKAPAAASTRRRPVVAKRDWAHVVDVNREIVNFHELVPDMAREYPFELDTFQ
KEAIYHMEVGESVFVAAHTSAGKTVVAEYAITLAQKHMTRAIYTSPIKALSNQKFRDFQR
TFEPSEVGILTGDVQINPEASCLIMTTEILRSMLYKGADLIRDVEWVIFDEVHYVNDLER
GVVWEEVIIMLPDHVGIILLSATVPNTKEFADWVGRTKKKDIYVISTPKRPVPLEHFLYS
GKELHKIVDSKGQFLGAGHKEATEAIRRKQDKEREAAGLGPPTRGGAAAGGRGGARGGAG
GGSNRGGGAAARQVAARGAMAAQRRAGTGPLNRMNNQSRDANLWIHLVGLLRKKELLPVV
VFTFSKKRCEEYASSMPNTDLCTAAEKSEVHITVERALTRLKGSDKLLPQIQNMRMLLSR
GVGVHHGGLLPIIVELLFARGLVKVLFATETFAMGVNMPAKCVVFSSIRKHDGRNFRELL
PGEYTQMSGRAGRRGLDKTGVVIINADADVPDTNTLSHMLLGQPTKLQSQFRLTYSMILN
LLRVEALRVEEMIKRSFSENAAQRLLPEHQQKVAEGENELKELRKLPPGPKTDDLKRFYD
LSQRIIELNTAVLDGVLAHPSSGRMMSAGRVVVLSDGHFRDHPAVLLKSAPPAVLPSGVI
DPTKQFFVLAFVPPEVRSGHHDVPVEAVPPRWPPRPSPVTDPSSLTYELAIVPLTSIALV
TSLALKVDADAIADRHRRSAMEAAVADYVALAESVGGELKEADWSKVRGLEFREALQERD
ELRKKLEFLAVEEEDLGEPYSILHSERVLEDKIASLRMALSDQNLELLPDYGQRIAVLKE
LQFIDDNSTVQLKGRVACEINSANELVLTELILDNVFASYEPEEVVALLSGFIFQEKTDV
EPLLTPRLEEGKATILATYDRVVAVQERHRANFADEGFNGSGELKFGLTEVVYEWARGMS
FHQITQLTDVQEGTIVRAITRLDETCREVRDAARVVGNAELYQKMLKAQEQIRRDVIFSQ
SLYFTGSTGSS