Protein Info for mRNA_207 in Rhodosporidium toruloides IFO0880

Name: 8575
Annotation: K01892 HARS, hisS histidyl-tRNA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 582 PF00458: WHEP-TRS" amino acids 32 to 79 (48 residues), 45.6 bits, see alignment 1.3e-15 PF13393: tRNA-synt_His" amino acids 94 to 381 (288 residues), 121.4 bits, see alignment E=9.8e-39 PF12745: HGTP_anticodon2" amino acids 481 to 579 (99 residues), 37.9 bits, see alignment E=3.1e-13 PF03129: HGTP_anticodon" amino acids 483 to 577 (95 residues), 43.2 bits, see alignment E=7.3e-15

Best Hits

Swiss-Prot: 60% identical to SYH_SCHPO: Histidine--tRNA ligase, mitochondrial (hts1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K01892, histidyl-tRNA synthetase [EC: 6.1.1.21] (inferred from 60% identity to spo:SPBC2G2.12)

Predicted SEED Role

"Histidyl-tRNA synthetase (EC 6.1.1.21) @ Histidyl-tRNA synthetase (EC 6.1.1.21), mitochondrial" (EC 6.1.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (582 amino acids)

>mRNA_207 K01892 HARS, hisS histidyl-tRNA synthetase (Rhodosporidium toruloides IFO0880)
MLLRSLTQRLTFATPRLARSVNPSAMSTVADLNARISEQGSLVRKLKEDKAAAEEVQKEV
LTLKELKAALAKLTGADDSKGKKGSKFTLKTPKGTKDWHPSDMYLRQAIFRKITDVFELH
GGVTIDTPVFELKEILSGKYGEDSKLIYDLQDQGGELCSLRYDLTVPFARFLAMNGTQYP
NIKRYHIAKVYRRDQPAMSKGRMREFYQCDFDIAGVYDPMLPDAECLAITCEVLEALDIG
EFTIKLNHRKILDGIFAVCGVPADKIRTISSAVDKLDKMPWEDVRKEMTEEKGLAGDVAD
RIGEYVKLKGGPELVEQLKQDERLTKNKSAVEGLNDMALLFKYLDIYGATPRVSFDLSLA
RGLDYYTGVIYEAVTEGSAPPVPVAPKPEAVPTPAQQKADVKGKKPALNADEEADIDEST
IGVGSIAAGGRYDELVGMFASGGAAGKIPCVGISFGVERLFSILLRKAQEKGETAGRAKA
TEVFVMSLGDGLLEERMKVCKELWAAGIKAEFMYKAKPKLPKQFEVIDKEKIPYAVQVSP
SELAKGTIRVKPQVGKELGSGNDIELKREELVPWLLEKLGKK