Protein Info for mRNA_248 in Rhodosporidium toruloides IFO0880

Name: 8616
Annotation: K01796 E5.1.99.4, AMACR, mcr alpha-methylacyl-CoA racemase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02515: CoA_transf_3
  • amino acids 9 to 332 (324 residues), 203.7 bits, E=2.6e-64

Predicted SEED Role

"Alpha-methylacyl-CoA racemase (EC 5.1.99.4)" (EC 5.1.99.4)

MetaCyc Pathways

• cholesterol degradation to androstenedione II (cholesterol dehydrogenase) (4/22 steps found)
• cholesterol degradation to androstenedione III (anaerobic) (1/22 steps found)
• bile acid biosynthesis, neutral pathway (4/29 steps found)
• superpathway of cholesterol degradation II (cholesterol dehydrogenase) (10/47 steps found)
• superpathway of cholesterol degradation III (oxidase) (5/49 steps found)

KEGG Metabolic Maps

• Bile acid biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.99.4

Protein Sequence (414 amino acids)

>mRNA_248 K01796 E5.1.99.4, AMACR, mcr alpha-methylacyl-CoA racemase (Rhodosporidium toruloides IFO0880)
MAAEGSRPLAGIRVLELAGLAPAPFAGLVLADYGADVVRVDRQGTSFNVDTLTRGKRSLA
VSLKSPEGISLLRTLLGPPSNGKDWRADILIDPFRPGVLERLGLDPKDLLAKNPRLIIAR
LTGFRREGPYAKMAGHDINYLALSGVLPMLGRKGDKPYFPANLLADFAGGGMMAVLGILA
ALIERTKSGKGQIVEIDMVTGTRYSSIFPLTMARPSLGLPMWSEPRGKNILDGGAPWYDV
YECKDAQYMSLGPIENHFYAKFLDIFIKNVPASIVPSPRPTASTQLDRSTWPSLVSFFTS
GFRTKTRDEWSRIFLGTDACCVPVLNRHEVDLEGRGPDEPDRLLGEEEAEDGGGLPMPTP
RLSRTPAKAGEAEEAFLEPGRDTVEILEAAGLGGKVDELVKAGAVGAGESRSKL