Protein Info for mRNA_255 in Rhodosporidium toruloides IFO0880

Name: 8623
Annotation: K02320 POLA1 DNA polymerase alpha subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1227 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR00592: DNA polymerase (pol2)" amino acids 106 to 1000 (895 residues), 797.7 bits, see alignment E=1.2e-243 PF03104: DNA_pol_B_exo1" amino acids 219 to 433 (215 residues), 86.9 bits, see alignment E=2.3e-28 PF00136: DNA_pol_B" amino acids 544 to 1002 (459 residues), 372.2 bits, see alignment E=5.8e-115 PF08996: zf-DNA_Pol" amino acids 1038 to 1221 (184 residues), 208.5 bits, see alignment E=1.1e-65

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1227 amino acids)

>mRNA_255 K02320 POLA1 DNA polymerase alpha subunit A (Rhodosporidium toruloides IFO0880)
MLEDMKPKRKGVDWRTATSALAAASAPIVASAEATDDSTAFNEEHKTVISSTAMRAPAHQ
TNALESDGSLQFWWFDYDEPAPGTVRLVGKVRVKNEQTRVAQIKDGKKVEKDVPKFVSAT
VVVKTIKRKLYVLPKTKAEYYGGEVDEDDSDDEDDELPFDDVEGDFLDDAKGKWNLKNVS
STQGYVKRRYAFGIKGVPRKETNWLEVTCDFPAGKRGESDIPIDAGGEQYSHVFGSTATA
FERFVVDHKIMGPCWLNISKPKVNKGDAFSWTKFEAEVDEKDISPFSSSDATAPKDVPRL
TVLSLSSRTVVHLKENKREIVCAAARVWHDVDIDDPTPVEHQGSSSKVFVRNLFTDFPTG
FDQQVRQHQGSPTFALFKAERPLLIQLLDYISRNDPDVIVGHDFSQLDLDVLLNRLRELK
IDNWSRVGRFRVKGDKWPQLRSGWNTGLLAGRLLLDLTSDGSKSLIDSTTWSLTEMCETH
LGIAREDVDPEDTAKFFDNVHSTAAHLKHFVLQCEADTYFQMAVAAKVQALPLTRQLTNL
AGNSWNRTLAGNRAERNEYILLHRFHETGYIVPDKISSREKKAQIDKAEKKKKKKTRDDN
GEEEPKVEVKREKYKGGLVFEPEKGLWDRYVLVMDYNSLYPSIIQEFDIDFSTIDWTADD
AEDLDKMPDRAPCDGEPQGILPQLIASLVARRRIVKGLMKDKSATVAKLMQYDITQKALK
LTANSMYGCLGYEGSRFYARPLAALTTFKGREILTRTKADAEGMSLNVIYGDTDSVMINT
NQTDYAAALKIGEDFKKVINDKYKKLEIDRDAVFERMLLLNKKKYAARKVEDDGKGGPGE
VTTEIKGLDMKRREFSKLSKDASKDVLDMILSAKATETVIEEIHEYLSDLGEKIRNGFKP
LDDYIIHKRLGKNPEDYPDAKSLPHVQVALKMKAKGLSAKAGDVIPYIFCVPPNGETTKT
AQAANAHHPDDVRRQGSTLKIDFEVYLSTQVLPPIERLCEHIEGTEKARLAECLGLDALR
FKSTSLDVPEREFKTLQSQISDAQRFADAEPFRIRCRTCGTISPFDGILENKAGMLSEHG
FFCGNIECQASLPTPSLAVQLDLQLRGFISRFYEAWLVCDEPTCGNRTRMMSVYGKKCLV
SGCRGAMHFEYSDAKLYDQLLYIDTLFDIERAIGKVAGGAQQGPVQTRIEANRHVLEQLR
RVVTKHLEKNGRRWVSMESLFSFMKVR