Protein Info for mRNA_357 in Rhodosporidium toruloides IFO0880
Name: 8725
Annotation: K01556 KYNU, kynU kynureninase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Kynureninase (EC 3.7.1.3)" in subsystem NAD and NADP cofactor biosynthesis global (EC 3.7.1.3)
MetaCyc Pathways
- NAD de novo biosynthesis II (from tryptophan) (7/9 steps found)
- superpathway of NAD biosynthesis in eukaryotes (10/14 steps found)
- L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde (3/5 steps found)
- L-tryptophan degradation I (via anthranilate) (1/3 steps found)
- L-tryptophan degradation III (eukaryotic) (6/15 steps found)
- L-tryptophan degradation IX (3/12 steps found)
- L-tryptophan degradation XII (Geobacillus) (2/12 steps found)
- L-tryptophan degradation XI (mammalian, via kynurenine) (9/23 steps found)
- superpathway of aromatic compound degradation via 3-oxoadipate (4/35 steps found)
- superpathway of aromatic compound degradation via 2-hydroxypentadienoate (5/42 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.7.1.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (531 amino acids)
>mRNA_357 K01556 KYNU, kynU kynureninase (Rhodosporidium toruloides IFO0880) MQASDKNAPLKTRLARLLAASGAVSLADPKLASYLDSNDPLGPFRAQFSFPKKRTLWPDA YRAEMEARGEADRDEDATECVYLAGNSLGLMPRRTPEMLSEELSVWSASGVLGHMDHAYG RPWIKIDETVTPILAEIVGAKPSEVACMGSLTGNLHTLFTSFYRPTPQRHKIMFEGKAFP SDAYAFASHIALHDYPPSSLLPVYPRSGEHNIRTEDILRLIEEEGDSIAVICFGAVQYYS GEWFDMEAITEAGRAKGCIVGFDCAHAVGNVPLELHDWGVDFACWCSYKYLNSGPGGIAG LFVHERWEDRKRLHGWWGHDKATRFAMPANYAPLPGAAGWQFSNPSVLDVVALLSSLQVF QEASRVLPRALAGGQISGRGPILGALREKSMDLTGYLELLLTSNPYYRAPSSFPPSSPSP AFTIITPLDPSRRGCQLSLLFHPVESMDWIFDRLRERGVLGDERRPGVIRFAPVPLYNSW SDVLQAAQALEEAIKAYEEWSRESGEVGEVAQALEETRIRPGVVEDEGLRQ