Protein Info for mRNA_499 in Rhodosporidium toruloides IFO0880
Name: 8867
Annotation: K00850 pfkA, PFK 6-phosphofructokinase 1
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00850, 6-phosphofructokinase [EC: 2.7.1.11] (inferred from 66% identity to uma:UM02512.1)Predicted SEED Role
"6-phosphofructokinase, fungal/animal type (EC 2.7.1.11)" (EC 2.7.1.11)
MetaCyc Pathways
- superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle (20/22 steps found)
- superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass (22/25 steps found)
- glycolysis III (from glucose) (10/11 steps found)
- glycolysis I (from glucose 6-phosphate) (10/12 steps found)
- homolactic fermentation (10/12 steps found)
- glycolysis II (from fructose 6-phosphate) (9/11 steps found)
- glycolysis IV (8/10 steps found)
- formaldehyde assimilation II (assimilatory RuMP Cycle) (7/9 steps found)
- superpathway of glycolysis and the Entner-Doudoroff pathway (12/16 steps found)
- superpathway of anaerobic sucrose degradation (14/19 steps found)
- 1,3-propanediol biosynthesis (engineered) (5/9 steps found)
- superpathway of hexitol degradation (bacteria) (11/18 steps found)
- hexitol fermentation to lactate, formate, ethanol and acetate (11/19 steps found)
- superpathway of N-acetylneuraminate degradation (11/22 steps found)
KEGG Metabolic Maps
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Fructose and mannose metabolism
- Galactose metabolism
- Glycolysis / Gluconeogenesis
- Pentose phosphate pathway
Isozymes
Compare fitness of predicted isozymes for: 2.7.1.11
Use Curated BLAST to search for 2.7.1.11
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (871 amino acids)
>mRNA_499 K00850 pfkA, PFK 6-phosphofructokinase 1 (Rhodosporidium toruloides IFO0880) MSANPLDRVAQQLEAILPGGGPKSPHLSGAETPPPFAFQSPGESQPQTPGKRRTRLACLT SGGDSAGMNAAVRAVVKMAIARGCEAYVVREGWEGLVRGNQDATAHAETPATSPPLAGAP TSIDPETSKKKRGGFVATYGEGELLKEGEGEQTLRGRYIIRVGWDDVRGFAAIGGTLIGT ARCAAFREVEGRRKAALNLVRHGIDALVVCGGDGSLTGADKLRAEWPEHMQALLENGDIT QDQYDTYKHLNIVGLVGSIDNDMAGTDMTIGATTALHRICDAVDSISSTASSHSRAFVVE VMGRHCGWLALMAAIATGADYMFIPERPPTAEDWQTSMCNVLSRHRDEGKRKTIVIVAEG AHDCNLNPITPNDIKDVLTNRLGLDTRVTTLGHTQRGGNPVAYDRILATLQGAEAVEAVL SSNPSTPSPVIGIRENKITRRPLMEAVAQTQEVAKAIEAKDFTRALSLRDPEFEDCLHAF RATTRLNTEYRVPESQRMRIGIIHTGAPAGGMNAATRTAVRYCLCHGHTPVAIYNGFAGL LEGNVAELTWLRVDQWGTRGGSELGTNRALPDSDMEGIAAKLAEYKIDSLFIVGGFEAMV AVNQLDKARDRYKALKIPLVHLPATISNNVPITEWSIGSDTSINVLVDACDAIKQSATAS RNRVFVVETQGAGCGYIAMLGALASGANIVYTPENGITLKQLVDDVEFLKRRYQQDVAGK SEGRLVIRSEKASKTYTTEVISNILAEEGKDLFDSRLVSLGHTLQGGVPSPRDRTRAVRL TVKCIDWLEQQHGSKTPGAASIAIQGAEIRFVPIAEMIAAADTKHRRGKVQWWTPMQRLV DVLCGRINLENEPLNAGIVPLAATTTATQTS