Protein Info for mRNA_709 in Rhodosporidium toruloides IFO0880

Name: 9077
Annotation: K08775 BRCA2, FANCD1 breast cancer 2 susceptibility protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1137 PF09169: BRCA-2_helical" amino acids 719 to 772 (54 residues), 35.2 bits, see alignment 1e-12 PF09103: BRCA-2_OB1" amino acids 776 to 897 (122 residues), 119.8 bits, see alignment E=6.8e-39

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1137 amino acids)

>mRNA_709 K08775 BRCA2, FANCD1 breast cancer 2 susceptibility protein (Rhodosporidium toruloides IFO0880)
MLPSSDPRGRGLEDDEDEGETVEGSHELANGTLKEGEAGEGADDSGVGLLPDIERSRDVE
EGVEAEPPDVDEVEDAEFEGDDMWLGFDDADVGFDQPDTFPSSAFSALPPPSDRLDGATA
DSDAHDAAFTEPSEPRLSDFGFANVNSLAGGTRGFVFATRKPLVVSEQAMQRMKAMLEAE
DHPADPPARPAERSQPVVRTKTPLARPLPLRQPTVPPAPAPPPAATSGLTLAAFGGFATA
GGTAVAAPSADAFALAQQRLQDSSSPAAANAFASSSTTAPTAASAFLGFQNAAGRSIDMP
SEEAMQRARAHLDAPSSSPPPSGGAPNRVMRLLRPKARLPVPTRDVFEAPPVVGRGSATT
GQPTFALPPPVSRAPSPIPIERIGDAMALDTPTALRVRQTSAKSSASDDGSLSAGRRTPL
LPLVNGGEKDGMQAKERAAEKDAETASSDTMRSSKSPPPPPVNDTAPSSDTIQSVAAPTP
VAPVARRPPVAPAVVSSAPSRPGSFRPPLLSHTATPARRPNSAYTPLHPSRLMSPASVAG
SSKPNPLLSQQRRLNFGMTPLRKPHHLANTRTATPGSGAGGKGFKTPWKDGKRPEGLTPM
GLKDKLAAQKASVKKVETSVKRDGEKRTSRLGEADLAKREKAKVFDLEANLGSERYDLTF
GMRPQTHYYEALQEIGLPDAVLDMDSTSGASYTFPCGRGVADAFSTLQALVCERMPQEKD
LVTLPWVKNHWSLILWKLASYVRSRPDLLDERWSFGRVMDQLRYRYEREVNRAERSAIKR
IQEQDSPASLPMVLCVSQIRWDEPSDGSGADPDTLVIVGLELTDGWYRIRTNVDRTLKSA
CERGKIVVGSKIAVMGAKLDCSKDEGSDVLQALGRSTLMITGNSTSLAPWHAKLGFRPEP
FVASLASISPAGGLVPLLDIYVDRAFPRGYTELRKGRSGENWGEEEEAARAKEWERGRKR
IEAKMTDELEKAGVEEDEIVELLREAVGRYDTAPTSTSLTEEPDEILDRLESAPNKQAII
RKLTAQQVQACFALAQENAQASRYRAVEDLQKELAEKYPPRQVRCFRVLRIFDAREGTRG
IKRTAQLTVWDAETFDADFFREGQRFMLSNTLPKGSWKPKDSEIGLATRRDSRWRRI