Protein Info for mRNA_854 in Rhodosporidium toruloides IFO0880

Name: 9222
Annotation: K01620 ltaE threonine aldolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF01212: Beta_elim_lyase" amino acids 44 to 322 (279 residues), 216.3 bits, see alignment E=3.1e-68

Best Hits

KEGG orthology group: K01620, threonine aldolase [EC: 4.1.2.5] (inferred from 46% identity to cci:CC1G_04438)

Predicted SEED Role

"Low-specificity L-threonine aldolase (EC 4.1.2.48)" (EC 4.1.2.48)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.1.2.48, 4.1.2.5

Use Curated BLAST to search for 4.1.2.48 or 4.1.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (428 amino acids)

>mRNA_854 K01620 ltaE threonine aldolase (Rhodosporidium toruloides IFO0880)
MTVPLPSVRLASSSTAAPPPLRPPLSSKERIARNQAKRVQVSRDFRTDTITIPTDELYEL
MKNASRGDSVYDEDEDTIELEQRIAEMAGKEAALFCVSGTMTNQLAIRTHLHQPPYSVVT
DHRAHVHISEAGGIAFHSLATTNAVYPRDGHHMTVEEVLDECVVDDDIHVAPTKLVCVEN
TLSGMVFPQSELVRLRSALDSFSIPLHCDGARMWEAMAKTGMSLSEACAPFHTVSLCLSK
GLGAPVGSILLGPKDFIRRATWFRKQFGGGIRQAGGLALAASVCLDTVLPQLPRTHYLAT
KLARALAAEGVQLDLPTETNMVWINPEPLGFSMTELQEAARAKAGITLGAPRGRVVVHYQ
IDERAIDELVEVVRELKAQRTEEARQWEEQVGLEIAEEIRRKSRLYAEGQYDGRIEGPKR
SLPAYGKR