Protein Info for mRNA_906 in Rhodosporidium toruloides IFO0880

Name: 9274
Annotation: K15791 DHKTD1 probable 2-oxoglutarate dehydrogenase E1 component DHKTD1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 966 transmembrane" amino acids 775 to 793 (19 residues), see Phobius details TIGR00239: oxoglutarate dehydrogenase (succinyl-transferring), E1 component" amino acids 49 to 961 (913 residues), 772 bits, see alignment E=4e-236 PF00676: E1_dh" amino acids 318 to 534 (217 residues), 142.8 bits, see alignment E=1.8e-45 PF02779: Transket_pyr" amino acids 603 to 815 (213 residues), 171 bits, see alignment E=3.3e-54 PF16870: OxoGdeHyase_C" amino acids 821 to 960 (140 residues), 136.6 bits, see alignment E=8.9e-44

Best Hits

Predicted SEED Role

"2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2)" in subsystem TCA Cycle (EC 1.2.4.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.2.4.2

Use Curated BLAST to search for 1.2.4.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (966 amino acids)

>mRNA_906 K15791 DHKTD1 probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 (Rhodosporidium toruloides IFO0880)
MLRSSLRIRPRPHALLSQTHRRSLHDRGIWGYEEPKTYTLPDFTPSELANRSQNASLLRL
VESYRRHGHRAALVDPLDLAQRPVVPALDPRRYGLGAEPERDEFVSETLAETGEDEGKKY
DTTGILDFPEDGKGSMRTMKEISQRLAEVYCGGVAYEFMHMPSKHERRFLETLLERSHAE
PISASEQLENWRLLARSEGFDQWAAKRFPNVKRYGGEGAESMMVAAAKILGEATKGGVED
VVIGMPHRGRLNLLTQLLSLDMRLLVRKMRGLPTLPPSLPPSQFTDDVLSHLFLSTRYTP
PSSSDSLTVHLLPNPSHLETVTPVALGFARGLQVPFGSLEAQKSGSSQPYELGSKVLSLS
IHGDAAFGGQGVVAESLNLASLPHFTCGGTVHIVVNNQIGYTTPATQGRSSFYATDLAKM
IAAPVLHVNGDKVDDVARAMKLALAYQQKFKKDVVIDLVVYRRRGHNELDEPAFTSPVMY
SKIKDLPSVAQLYEQHLVSQSTLSSSDAASYRKSHFASLDEALAAADPEKFTPPELEMPR
GWAEMRWPKEGEWETQVDTGYDQQVLREIGERSVQVPDEITIHPRLLKMHIRKRLDSLKE
GAGIDFATAEALAFGSLLLEGNHIRLCGQDSGRGTFSQRHAILADQTSERVAVPLQTLTS
SPPSSSSSSTQPGTIEVVNSPLSEYAPLSFEQGLAYVSPKMLPIWEAQFGDFHNTAQVTI
DTYLGGGETKWGMQSALTLLLPHGQDGAGPEHSSSRIERFLQLTNEPLSRSKPFVPNMHL
VNVTTAAQYFHLLRRQMKRDYRKPLVVFSPKGILRLPAASSRLAEMAPGTTFQPVLTEQV
ADPSTVERVVLLSGKMYFELAKQRAERKLDGQIVFIRVEEISPFPYKAFSDALAPFPSAK
SIAWAQDEPENAGAYLFVLPRLQQILPRGLELEYIGRDAMATPAPGVKKYFEEQRKDIEE
RIFAGL