Protein Info for mRNA_958 in Rhodosporidium toruloides IFO0880

Name: 9326
Annotation: K14541 DUR1 urea carboxylase / allophanate hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1239 PF00289: Biotin_carb_N" amino acids 7 to 108 (102 residues), 116.4 bits, see alignment E=3.8e-37 PF02786: CPSase_L_D2" amino acids 114 to 319 (206 residues), 195.6 bits, see alignment E=3.2e-61 PF02222: ATP-grasp" amino acids 130 to 290 (161 residues), 21.4 bits, see alignment E=6.4e-08 PF07478: Dala_Dala_lig_C" amino acids 141 to 290 (150 residues), 36.3 bits, see alignment E=1.8e-12 PF02785: Biotin_carb_C" amino acids 343 to 450 (108 residues), 114.4 bits, see alignment E=1.1e-36 PF02626: CT_A_B" amino acids 483 to 762 (280 residues), 252.8 bits, see alignment E=1.9e-78 PF02682: CT_C_D" amino acids 829 to 1045 (217 residues), 115.7 bits, see alignment E=1e-36 PF00364: Biotin_lipoyl" amino acids 1178 to 1236 (59 residues), 23.5 bits, see alignment 1.6e-08

Best Hits

Predicted SEED Role

"Biotin carboxylase of acetyl-CoA carboxylase (EC 6.3.4.14)" in subsystem Fatty Acid Biosynthesis FASII (EC 6.3.4.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.3.4.14

Use Curated BLAST to search for 6.3.4.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1239 amino acids)

>mRNA_958 K14541 DUR1 urea carboxylase / allophanate hydrolase (Rhodosporidium toruloides IFO0880)
MSATKQHKLLIANRGEIALRCMRSAAALKIPTVAIYMEADASAPHVFKADEAALVPAYID
QDAVLNVCREKGVTMIHPGYGFLSENEAFAAKVEKAGIIWLGPTPSQIEAMGLKHEARAR
AIKADVPVLPGSELVETLDLALEQASKVGYPILLKATAGGGGMGMSICGSEGELKKAFQG
TTDLSKNLFSNAGVFVEKYIPKARHIEVQVFGDGKGKVIHCGERECSAQRRQQKVLEEAR
SPFIMRHPDLGDAMCAAAVRLCELIDYRSAGTVEFIVDDSNASYYFLELNSRIQVEHAVT
EMVRPGLDLVGMMIRLGLSQDGSSAFSLPPQGEVAEAHGHAIEARIYAEIPHLNFKPSPG
LLQEVKWPAPQDYIRIDTWVDSGSMISPFFDPMIAKLITYGSTRDEARSRLDKALADTSL
LGTTTNLAYLREIVNCDEFKHGDVTTKFLDSYEYLPSCIEVVDGGLSTTVQDGRPRLLPG
GDGIPRSGFSDELAAKAANLLVGNPEETEVFEATVSGPSLKFSTAAVVAICGATADIFLD
DTPKPMWTRFVVPAGSTVEVGGCEGTGNRVYIAVRGGFPEVPLFLGSKSTFTAAKLGGIQ
GREVVAGDIITLSPSAAPTSADEKDFTLPSNSLPSYPSEWTLSALPGPQADDDYLTEEDR
QTLYSSTFTVSPASNRLGLRFDGLKPLKYSPRRQDGGRAGSHPSNCLEHGYTVGSLNMNG
DTPVLLGMDGPDCGGLICILGVVGSDWWKLGQMSAGDTFRFVLPSTTTLPSHVAKQQQWL
EAVKQAVKSGSTSDLPSFPLDVETQPQPVTDGVVKVIEGDAALDAPKLTFRLAGDGGILI
EVGEQDLFFRTRLIVELWERRLKAKKHEGLYTYIPGVASMLVKFHPDLISQDELLDLLVS
TSEGLARESLDQVVPSRRIQLPVCFDDAGTKDVIEQYMTSTGRKKAVYLPSNIDYLAQAN
AFDGVDDIAKTLASADWYVCSRSFFAGLPMIAPLDQRCVLASQKYNPTRTFTQRGALGYA
GCLAAIYPVESPGGYQLLGRTLTPFSVAGRYGGSGHEKHFLLRNFDVVACLPMSEEEFNK
VEKDFDAGAFKPTIEEYSISAKEMIAFEESTRSAVQALAKKRKEGFQALAKQEAIYVAEY
QAEQQKAKEAEAAAASSGGGKIGSMSGTPLKSPVQATVRSIGVKVGDELTADTSAIVLEA
MKTQISVKLSRTLLGKKVTGIAVEMGDVVKPGQPLLYAE