Protein Info for mRNA_997 in Rhodosporidium toruloides IFO0880

Name: 9365
Annotation: K08735 MSH2 DNA mismatch repair protein MSH2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 986 PF01624: MutS_I" amino acids 26 to 135 (110 residues), 55.7 bits, see alignment E=1.5e-18 PF05188: MutS_II" amino acids 152 to 291 (140 residues), 72.8 bits, see alignment E=9.2e-24 PF05192: MutS_III" amino acids 309 to 644 (336 residues), 127.8 bits, see alignment E=1.6e-40 PF05190: MutS_IV" amino acids 507 to 603 (97 residues), 62.4 bits, see alignment E=1e-20 PF00488: MutS_V" amino acids 701 to 894 (194 residues), 265.6 bits, see alignment E=7.3e-83

Best Hits

Predicted SEED Role

"DNA mismatch repair protein MutS" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (986 amino acids)

>mRNA_997 K08735 MSH2 DNA mismatch repair protein MSH2 (Rhodosporidium toruloides IFO0880)
MPALQYSKEKKDKEQEQKDKAEEDRFVKAFAKLPARPAGTIRLFDRSEFYCAYGEDAFFV
ANHHYKTQTVLKYLGSNEDGLPSVTLSHAVAQAFLRDALTTKQLRVEIWEPESGGVGRGS
TKWKLVKAASPGNLGPVEDLLFTYTDLLASPVLVAIRLQVKDNVKTIGVAFADTSMQELG
VSEYVDNELFSNTEALLIQLGAKECLVIEQDKAHEYDLNKLKTLIERCGVVITERKKSEF
TSGSVEQDLNRLLRGSLQAASRPEFDHKIAMSAVAALISYLALMQDSSNFGAYALRTHDL
SMYMRLDASALRALNLMPDPTGLGNSSKTMSVFGLLNRCKTAQGTRLLAMWLKQPLVNRH
VILQRQDLVECLVESQEFRQAITDDFLKSMPDFHRISKRFQKGAASLEDVVRVYQAVLLL
PGLVTVLERGVEVEDEDGDAEMQDGEQVENGAEKEESREKRWKGLIEELWLQHLRTHNES
LLPYQEMVETTIDLSELDRHNFVIKPDFDKSLAAIREKLEAVRDGLNEEHEEVARDLGME
PDGKVLHFEQTTLYGYCFRLTRKESAVIRNKKNYIELKNQTNGMYFTTKALKQLNDEYRD
CTKEYEKKQSQLVKEVIQIASSYCEVLETLNTVIAHIDVITSIATSSLNAPIPYTKPTIF
ERGGGSLKLEEARHPCLEVQEGIDFIANDCHLERDVSEFSIITGPNAGGKSVFIRQTAVV
ALLAQIGSFVPCSFAEIPIFDSILCRVGAGDSQLKGVSTFMAEMLETSAILRQATRDSLV
IIDELGRGTSTYDGFGLAWAISEHLSTVTRASVLFATHFHELTALANQVPHVKNLHVVAH
VESNPDTLTGKDITLLYKVMPGICDQSFGIHVAQLANFPDEVVKLAKRKADDLEDFTEKP
ESADAAEPAIAHLSPEAIAEGTALVEAFLETWASRTAELPAAAADEAPAGETREDVELKE
LVRCFEEYQSKFEGSGWTREVLAKTY