Protein Info for mRNA_1066 in Rhodosporidium toruloides IFO0880

Name: 9434
Annotation: KOG1383 Glutamate decarboxylase/sphingosine phosphate lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00282: Pyridoxal_deC
  • amino acids 1 to 238 (238 residues), 156.5 bits, E=4.3e-50
• TIGR01788: glutamate decarboxylase
  • amino acids 1 to 341 (341 residues), 383.9 bits, E=4.5e-119

Predicted SEED Role

"Glutamate decarboxylase (EC 4.1.1.15)" in subsystem Acid resistance mechanisms (EC 4.1.1.15)

MetaCyc Pathways

• L-glutamate degradation IX (via 4-aminobutanoate) (1/1 steps found)
• GABA shunt (3/4 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Butanoate metabolism
• Glutamate metabolism
• Taurine and hypotaurine metabolism
• beta-Alanine metabolism

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.15

Use Curated BLAST to search for 4.1.1.15

Protein Sequence (394 amino acids)

>mRNA_1066 KOG1383 Glutamate decarboxylase/sphingosine phosphate lyase (Rhodosporidium toruloides IFO0880)
MKKMWQARRKAAGKSWKGEGNIMMGANSQVALEKFARYFDQEMRQVPVDELTKYVMEPKR
AIELVDENTIGVYVILGSTYTGTYENVEEMSRLLDEYEAKTGHYVPIHVDAASGGFVAPF
ASPSLKWDFRIPRVVSINSSGHKFGQSYVGCGFIVWRDKQHLPKELVFELHYLGSVEYSF
SLNFSRPAAPFLAQYFNLLYLGFEGYRRVALNDLKNARLLARALERSKYYKAVSEVHHLK
DRSLTEKAKETVGAVDDVEAYVPSLPVVAFMFSDEFGKEYPRIKQRSIQLGLREHNWIVP
NYDLPPNAQDKEVLRVVIRENFNEDMVERLFHDIIEVTEQLMDEHKADVRQPGEGEGRNV
NAPKHGKGKEQLVSERMAASHGEGTRPVGHDSVC