Protein Info for mRNA_1161 in Rhodosporidium toruloides IFO0880

Name: 9529
Annotation: K03028 PSMD2, RPN1 26S proteasome regulatory subunit N1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 940 transmembrane" amino acids 516 to 531 (16 residues), see Phobius details amino acids 552 to 569 (18 residues), see Phobius details amino acids 671 to 688 (18 residues), see Phobius details amino acids 710 to 728 (19 residues), see Phobius details amino acids 742 to 760 (19 residues), see Phobius details amino acids 782 to 796 (15 residues), see Phobius details amino acids 808 to 825 (18 residues), see Phobius details amino acids 837 to 855 (19 residues), see Phobius details PF17781: RPN1_RPN2_N" amino acids 56 to 396 (341 residues), 396.8 bits, see alignment E=1.6e-122 PF01851: PC_rep" amino acids 521 to 553 (33 residues), 22.8 bits, see alignment (E = 1.8e-08) amino acids 745 to 776 (32 residues), 23.9 bits, see alignment (E = 8.3e-09) PF18051: RPN1_C" amino acids 875 to 928 (54 residues), 98.2 bits, see alignment 4.5e-32

Best Hits

Swiss-Prot: 55% identical to RPN1_SCHPO: 26S proteasome regulatory subunit rpn1 (rpn1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K03028, 26S proteasome regulatory subunit N1 (inferred from 57% identity to tml:GSTUM_00003152001)

Predicted SEED Role

"proteasome regulatory subunit Rpn1" in subsystem Proteasome eukaryotic

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (940 amino acids)

>mRNA_1161 K03028 PSMD2, RPN1 26S proteasome regulatory subunit N1 (Rhodosporidium toruloides IFO0880)
MPIEEKERPQAMVSVPSKDPEPPKKDRAADNLLKAKQELKQDTELNEEDQALKGELEMLV
ERLRESDTSLHRPALESLRTLIRTSTSSMTSVPKPLKFLRPHYAELAKIQASWPDQPVAS
TSQAIAQTATAAVETVAAAVGLGGKDAAVNGDKKDESQVQVTDKGLFADILSVLAMTYSD
TGKRETLMYRLKGGSDEDPGVWGHEYVRHLAAEIGEEYAARQEKEESTEDLLALGLRLVP
FLLTHNAESDAVDLLLELESIDRIVDHVDSNTYQRVCLYMVSMVYYLTPPDDVDFLKTAR
AIYKKHSRYTEALTLALRLQDMDMIKEDFEAPTNPQMKRQLAYILARQQINVETDDETLT
EILNNTKLSENFKRFGQELSVTEPKSLEDIYKSHLENSRNPTQVDSAKQNLAGTFVNAFV
NAGFGNDKLMVEAEEGQSWIYKNKDHGMFSAAASLGLSLLWDTDVGLSHIDKYAYASEDY
IKAGAMLANGLIHSGVRTEMDAALALLSEHVEATSVPLRVASIIGIGIAYAGSKREDIRD
ILLPSLQDSSVSMEIASMAALALGFVFVGSCDEDVTMGVVSAMMERDEAQLKEKWGRFLA
LGVALLYLGRTEQSEATIEVLKTIEAPLGKVAITLVQSASYAATGNVVEIQKLLKEATDH
LDPEKESDLHQSMAVIGVALIAMGEDVGSQMSIRHFNHLMHYGEPVVRRAVPLALGLISA
SNPAMHILETLSRYSHDNDLDVALNAIFAMGLVGAGTNNAKLAQMLRQLASYYSKEPDCF
FMVRIAQGLVHMGKGTIGINPFHTDRSLVSPVAVCGLLATMLAFTDTRGFILEKSHWMLY
FLTMAMYPRFLITLSDETNELLPTSVRVGQAVDVVGQAGKPRTISGFQTHTTPVRLGHTE
RAEMATEEYLPYSHVLEGYVLLAKNKGYEKDADDMEVEKK