Protein Info for mRNA_1169 in Rhodosporidium toruloides IFO0880

Name: 9537
Annotation: K01469 OPLAH, OXP1, oplAH 5-oxoprolinase (ATP-hydrolysing)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 761 PF05378: Hydant_A_N" amino acids 18 to 243 (226 residues), 178.4 bits, see alignment E=1.1e-56 PF01968: Hydantoinase_A" amino acids 262 to 562 (301 residues), 316.4 bits, see alignment E=1.9e-98

Best Hits

Predicted SEED Role

"5-oxoprolinase (EC 3.5.2.9)" in subsystem Glutathione: Biosynthesis and gamma-glutamyl cycle (EC 3.5.2.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.9

Use Curated BLAST to search for 3.5.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (761 amino acids)

>mRNA_1169 K01469 OPLAH, OXP1, oplAH 5-oxoprolinase (ATP-hydrolysing) (Rhodosporidium toruloides IFO0880)
MPSILPAYSLPDHSVQVSTDRGGTFTDVHASWPQENGERKEIIFKLLSVDPSHYADAPTE
ACRRVLELATGTKIPRGVKLETNKFDYIRLSTTVATNALLERKGAPHVFVTTKGFRDLLR
IGNQSRPNIFALNVRRAEVLYESVLEVDERVTLHGYTYDPDFEENAPKFDEAGKLISDHK
GEFVRGISGEAVQILRKPDLAKVRSDLQAIYDRDVRSVAICFVHSFTFPDHENLVADICR
DIGFPQISVSSALSPQIKAVPRATSASVDAYLNPVLKDYLRGFFKNFESSLADGTSGARV
EFMTSEGTLVDVAHFSGLRSILSGPAGGVVGYSLTSWDEKESGNRPICGYDMGGTSTDVS
RFDGRFEKTYETTTAGVSIQCPQLDINTVAAGGGSCLTFRNGLFRTGPESAGAHPGPACY
RKGGPLAITDANLVLGRLFPQYFPHIFGPSEDQPLSREDSVKAFEELMREINAYNVKHGD
GKVMTLDEVAYGFIKVANETMARPVRALTEAKGLSTSKHILAAFGGAGGQHACELARTLG
ISTILIHRYSSILSAYGMALSNRAFEKQEPCAAEYNDANKPALLDRIERLRTQVVEELRR
QGFAEHRIDVECYLNMRYDGSDTSLMTLAPADGSFDYQSAFEAMYRAEFGFLIEGKAVMV
DDVRVRGIGRTFDSLGESVHAEVRKTTFSSAGVDAKAEKSRTSMYFEQTGRVDVPVYLLD
NLATGDLVEGPSAIVDGTATLILDPGASAKICSRHVYITLA