Protein Info for mRNA_1235 in Rhodosporidium toruloides IFO0880

Name: 9603
Annotation: K12818 DHX8, PRP22 ATP-dependent RNA helicase DHX8/PRP22

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1272 PF00575: S1" amino acids 263 to 330 (68 residues), 33.7 bits, see alignment 9.2e-12 PF00270: DEAD" amino acids 576 to 727 (152 residues), 25.1 bits, see alignment E=3.5e-09 PF00271: Helicase_C" amino acids 768 to 899 (132 residues), 47 bits, see alignment E=7.7e-16 PF04408: HA2" amino acids 961 to 1050 (90 residues), 82.1 bits, see alignment 8.5e-27 PF07717: OB_NTP_bind" amino acids 1108 to 1184 (77 residues), 79.9 bits, see alignment 3.7e-26

Best Hits

Predicted SEED Role

"RNA helicase, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1272 amino acids)

>mRNA_1235 K12818 DHX8, PRP22 ATP-dependent RNA helicase DHX8/PRP22 (Rhodosporidium toruloides IFO0880)
MANELEKLELLSLVNSITNELVNYTGLSDSTLAEFLIHLHGDSKDFNTFKSKCRDVGADF
PDSFLSSVDRLILSMHPKYKLKSKSSSSKDKGKGKEEGEKAVMSEEKQKQARLFPGLAMP
DTEWQPSYRADNPEEVKERQMRMGQPADVKGVSDDLRSRDEDNMGVDDLMAQLEGVRKRA
TRPEEDDRRDGGADAKRQRHRSPDYERREGGGGGRERDNGYGDRGRSGSSRYGEDDRGRY
GRDGRTGGAGAGRLDEKPVLYKIYKGRVVNIKDFGAFVTLEGVQGKAEGMVHIGSISTGR
VSHPSDLLARGQSVFVKVMSVAGNRLSLSMKDADQRTGADLSPHLRIKTEEELFEETRRA
AERAATGANGVAVRKSFADDNRTASVRRMTSPERWEIKQLIASGAASAADYPGLDDEYIN
SGFETGPGGKSLVDEADEELDVEINEAEAPFLAGQTKRALELSPVKIVKAPDGTMNRAAM
AGAALAKERRELKAQEASDQADSEARDVNTPWLDPMTAPHERAFAADARGQAAGQRAKDV
PAWKKDTFNPATTFGKITSMSIADQRKSLPIYKFRDQLIEAFANNQVLVVVGDTGSGKTT
QMTQYLAEAGYADRLKIGCTQPRRVAAMSVAKRVAEEVGCRLGQEVGYTIRFEDCTSPET
KIKYMTDGMLQRECLVDPDMSQYSVLMLDEAHERTIATDVLFGLLKKSLKRRPDLKLIVT
SATLDAEKFSEYFFGCPIFTIPGRTFPVEILYTKEPEPDYLDAALITIMQIHLSEPPGDI
LLFLTGQEEIDTSCEILYERMKSLGPNVPDLIILPIYSALPSEMQSRIFEPAPPGARKVI
LATNIAETSLTIDGIYYVVDPGFVKQNAYDPRLGMDSLIVTPISQAQARQRAGRAGRTGP
GKCYRLYTEAAYRNEMLPNSIPDIQRQNLAHTILMLKAMGINDLLNFDFMDPPPQQTMIT
ALENLYALSALDEEGLLTRLGRKMADLPIEPPLAKMLIASVDLECSEEILTIVAMLSVGG
TIFYRPKEKQAQADAKKAKFHQPEGDHLTLLTVYNGWAASKFSNPWCSENFIQGRAMRRA
QDVRKQLLGIMDRYKHDILSCGKNYNRVRRAITSGYFRHAAKKDPQEGYKTLVEGTPVFL
HPSSALFNRAPEWCVYHELVLTTREYMREVTAIEPKWLVEVAPAFFKVADQNTISKRKKQ
EKIQPLFDKCVWPFSFRSSRGKGGGTMEVEMLGVSGGAPLGSAGGLRLKYAEHQDAWRLS
KLKRATRSSQTF