Protein Info for mRNA_1374 in Rhodosporidium toruloides IFO0880

Name: 9742
Annotation: K01733 thrC threonine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 593 PF14821: Thr_synth_N" amino acids 5 to 84 (80 residues), 95.9 bits, see alignment E=1.3e-31 TIGR00260: threonine synthase" amino acids 71 to 315 (245 residues), 220.9 bits, see alignment E=1.3e-69 PF00291: PALP" amino acids 99 to 342 (244 residues), 46.9 bits, see alignment E=2.7e-16

Best Hits

Predicted SEED Role

"Threonine synthase (EC 4.2.3.1)" in subsystem Threonine and Homoserine Biosynthesis (EC 4.2.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (593 amino acids)

>mRNA_1374 K01733 thrC threonine synthase (Rhodosporidium toruloides IFO0880)
MPSLKYISTRGGDEKLSFEEAVLRGLAPNGGLYIPAHLPHLPENWEQDWAKLSFTDLALE
LYSLFISEKEIPRDDLRDLIERSYLTFRHEQVTPIHRTGDKEFILELFHGPTFAFKDVAL
QFVGNLFEYFLARRNAGKPEGQRDRLTVVGATSGDTGSAAIYGLRSKKDISIFILHPKNR
TSPIQEAQMTTILDDNVFNLAVDGTFDDCQDIVKSLFNDMEFNSRYHLGAVNSINWARIL
AQTAYYFAAYFAVQSQIPYDVLEPKIQFCVPTGNFGDVLAGWYAKHLGLPMAKLVVATNA
NDILARFWKTGRYEKADSGEPEYFTDDEDDTEEVRPSRYPGLTEDEAFRRQQEAVAQSVQ
LNGASDGKQALGNAFRSPSAVRRAAAAAGTVAETLSPAMDILVSSNFERLLFYLALEGTT
AGAVAADGEVDGGQAARVRMAAENVRVWMDKLKTEHKVKVPRACVEAARRDMIADRASDD
ETSQTIRKYYAKKDEYGSYVVDPHTAVGLSVANRVAKENDPNIIQFDGAVSSALANEPGF
DFKRDVLPKEMEGLLEKPRRCKDVKNDREAVKRIIEEEVGRLFASQTIGASGL