Protein Info for mRNA_1659 in Rhodosporidium toruloides IFO0880

Name: 10027
Annotation: K08741 MSH5 DNA mismatch repair protein MSH5

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 971 transmembrane" amino acids 252 to 273 (22 residues), see Phobius details PF05192: MutS_III" amino acids 308 to 621 (314 residues), 93.9 bits, see alignment E=1.5e-30 PF00488: MutS_V" amino acids 694 to 902 (209 residues), 141.4 bits, see alignment E=3.6e-45

Best Hits

Predicted SEED Role

"DNA mismatch repair protein MutS" in subsystem DNA repair, bacterial MutL-MutS system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (971 amino acids)

>mRNA_1659 K08741 MSH5 DNA mismatch repair protein MSH5 (Rhodosporidium toruloides IFO0880)
MPSLGSATAARAVRPSPTPPTSHQFDETNSRSNARHIHWGAEEVYEDDAEPEGEGANEME
GEEEQLKDGLVLAITAAKSKVACCYFESTSDKIYFLEDQQDSSEWDLTALVLEQLAPKFV
LTCANADADFLQAVEEKLSSLAPDSSTASSLGPDGTPVRIEYRPNRDFYAGSGKNALYRV
HITEGGWYAPAEDEVIGSDSGSTHGQQDDSNDFALGDAYDFGRPCAKRRKVAHNQDDGDR
ARRNSELRIETFLSNLAACPLTLGCAGALLGYITRQRTEAGELENDLFEVSGLELMRLDK
VMHINSDALTSLQIFCEESHASAHSRSTKEGLSLFGIVNIAHTPLGRALMRQWFLRPSLE
LDVIESRQAAVECFLRESNQHIVDAICKHLRNVKNTPRQLKALASGKSTIKEWQAVWSLI
YAAIMIRDAASQLVHKNGVEVIDKLAAAYDVAQIKEIADMINDIIDWEESARQNGKVCVR
PGVDATLDELRRKYNGLGSLLSKVAVEISQEVPPGLADELSVVYFPQLGYLITIAYEPEV
TDAGKYGQFGWDFQFVTEMQAYFKNDKCRDMDRHLGDLQSFISDKEIEIIDALLSHVLAI
RDQLLASVAIFSELDCLIAFAEAAKLYNWTRPVMTEEPVCKILKGRHPLSELCVDTFVPN
NTSLTGGLGIKRSADGVDEKPDLHEISQDEKSVIIVTGANFSGKSVYLKQIALLTFMAHI
GCFVPAEEALIGLADRIMTRVSTKESITRGSSAFMIDLQQISFALRNLTPRSLLIIDEFG
KGTEPDDGAGLFCGVVDHLVGLGSGTPRVAIATHFQHVFTNGLLSRQLPIFLAHMEVLVV
EPSSDRRGRDGRRGGGREFDELTYLYRLAPGLSLSSHALSCSSLFGIPPTLLSRASTITH
ALSTFSLDSLILANEMDEDERRELCEAEGVGRRFVGWEVPAEGEGEMEAEEVRALVRSLL
EVEGEGEREDA