Protein Info for mRNA_1675 in Rhodosporidium toruloides IFO0880
Name: 10043
Annotation: K01424 E3.5.1.1, ansA, ansB L-asparaginase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 39% identical to ASPG_HELPY: Probable L-asparaginase (ansA) from Helicobacter pylori (strain ATCC 700392 / 26695)
KEGG orthology group: K01424, L-asparaginase [EC: 3.5.1.1] (inferred from 51% identity to ani:AN0300.2)Predicted SEED Role
"L-asparaginase (EC 3.5.1.1)" in subsystem Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 3.5.1.1)
MetaCyc Pathways
- L-asparagine degradation I (1/1 steps found)
- superpathway of L-aspartate and L-asparagine biosynthesis (3/4 steps found)
- L-asparagine degradation III (mammalian) (2/3 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.1
Use Curated BLAST to search for 3.5.1.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (393 amino acids)
>mRNA_1675 K01424 E3.5.1.1, ansA, ansB L-asparaginase (Rhodosporidium toruloides IFO0880) MFVKASLALAAAASLLGTTSAAPLASSFVERSLVERAPVTSVDFNVTYKSNYTEHLPKTL ILATGGTIAGSSSSATDSTAYTAGVVGIGVLVEAVPQLLNVSNIDGMQVSNVGSESLTDE IALRLSKLANKALCAADAPYDAVVITHGTDTLEETAFFLDITIGCDKPVVVVGSMRPSTA ISADGPNNLLQAVTTAVSPNSRARGTLIVLNDRICAAYYCEKTQANTLNTFASPEPGYIG GLLSDKPFYYMGASKPTFKQVFDISNVTELPHVEIFYSYQGADFELLNTTVANGAKGVVI AGTGAGSLTDAGMTNVDATVSSGVPVVRSTKINVGFVTPGDYPNTIASGSLNPVKSRRQL QVLLALNKTNDEIRTAFEEPLKTYLNFNISSYY