Protein Info for mRNA_1830 in Rhodosporidium toruloides IFO0880

Name: 10198
Annotation: K00809 DHPS, dys deoxyhypusine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 TIGR00321: deoxyhypusine synthase" amino acids 23 to 352 (330 residues), 371.5 bits, see alignment E=1.7e-115 PF01916: DS" amino acids 37 to 351 (315 residues), 439.4 bits, see alignment E=2.9e-136

Best Hits

Swiss-Prot: 60% identical to DHYS_DICDI: Probable deoxyhypusine synthase (dhps) from Dictyostelium discoideum

KEGG orthology group: K00809, deoxyhypusine synthase [EC: 2.5.1.46] (inferred from 68% identity to scm:SCHCODRAFT_63456)

MetaCyc: 59% identical to deoxyhypusine synthase (Solanum lycopersicum)
Deoxyhypusine synthase. [EC: 2.5.1.46]

Predicted SEED Role

"Deoxyhypusine synthase (EC 2.5.1.46)" (EC 2.5.1.46)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.5.1.46

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (366 amino acids)

>mRNA_1830 K00809 DHPS, dys deoxyhypusine synthase (Rhodosporidium toruloides IFO0880)
MSGPDAAKAAVFVQSEQYEGTRIKGPDFNEPQTLESLLQSYERIGFQANGLARAMELVDK
MRNWRLSDEPVNPDLQTEELDPEVRANTRCSIFLGYTSNLVSSGLREIIRFLVQHKYVSC
LVTTAGGIEEDLIKCLGPTFLAPRGDFNQDGAGLRRRGLNRIGNLLVPNDNYCKFEDWVM
PILDKMVEEQETGDKVRWSPSKVIDRLGKEINDESSILYWAHKNQIPVFCPALTDGSLGD
MIYFHTYKTETPLSIDIVSDIRRLNDLSIKSKKAGMIILGGGVCKHQIANSMLFRNGADF
SVYINTGQEFDGSDSGARPDEAVSWGKIRIDGESVKVYADATLVFPMLVAGTWGKAHWAK
EEKERK