Protein Info for mRNA_1838 in Rhodosporidium toruloides IFO0880

Name: 10206
Annotation: K04486 E3.1.3.15B histidinol-phosphatase (PHP family)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01856: histidinol phosphate phosphatase, HisJ family
  • amino acids 52 to 312 (261 residues), 219.5 bits, E=3e-69
• PF02811: PHP
  • amino acids 54 to 266 (213 residues), 42.2 bits, E=5.6e-15

Best Hits

KEGG orthology group: K04486, histidinol-phosphatase (PHP family) [EC: 3.1.3.15] (inferred from 49% identity to uma:UM03583.1)

Predicted SEED Role

"Histidinol-phosphatase (EC 3.1.3.15)" in subsystem Histidine Biosynthesis (EC 3.1.3.15)

MetaCyc Pathways

• superpathway of histidine, purine, and pyrimidine biosynthesis (38/46 steps found)
• L-histidine biosynthesis (9/10 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Histidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.15

Protein Sequence (366 amino acids)

>mRNA_1838 K04486 E3.1.3.15B histidinol-phosphatase (PHP family) (Rhodosporidium toruloides IFO0880)
MLTLLRYCPQRLLDASLDFISFESSPTRQPPPRRAATATHCRGAHCTSRMTISHHSHSGE
FCCHAKGTLAEVVDEAIRQGFTTFGLSEHVPRYELSHLYPEEAHLTTQDLAQTFDKYLVE
AHRLKKLKADELSILVGLETEYIDERGLDELERLLARKGEAIEYLVGSVHHCDEQPIDFD
KERFDGCLASQTGSSEHDRLSRLFATYFDNQLELMKRLEPEIIGHFDLCRLYYPDTDFRS
FPEVWSRIERNVDFAVNYGGLFEVNASAFRKGWSTAYPGVEVFDLILRKGGRFTLSDDSH
GPQAVGLHYDRAYAYLRERKVEELWRLVPASRWGESAKRGAVVEKIEGRPWSDSWPELLK
ERSKQQ