Protein Info for mRNA_1891 in Rhodosporidium toruloides IFO0880

Name: 10259
Annotation: K03083 GSK3B glycogen synthase kinase 3 beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00069: Pkinase
  • amino acids 39 to 333 (295 residues), 213.8 bits, E=3e-67
• PF07714: Pkinase_Tyr
  • amino acids 42 to 252 (211 residues), 88.3 bits, E=5.4e-29

Best Hits

Swiss-Prot: 68% identical to GSK1_MAGO7: Glycogen synthase kinase 1 (GSK1) from Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)

KEGG orthology group: None (inferred from 79% identity to uma:UM00560.1)

Predicted SEED Role

"Low-specificity L-threonine aldolase (EC 4.1.2.48)" (EC 4.1.2.48)

MetaCyc Pathways

• glycine biosynthesis IV (1/1 steps found)
• L-threonine degradation IV (1/2 steps found)
• superpathway of L-threonine metabolism (11/18 steps found)

Isozymes

Compare fitness of predicted isozymes for: 4.1.2.48

Use Curated BLAST to search for 4.1.2.48

Protein Sequence (402 amino acids)

>mRNA_1891 K03083 GSK3B glycogen synthase kinase 3 beta (Rhodosporidium toruloides IFO0880)
MTPPLSSTHTNTNTADESQKLVKVIASNGRTGEQCELSYSSTKVVGNGSFGVVFAAKLAP
GSLGPDNEGDDDVAIKKVLQDKRFKNRELQIMRVVRHPNVVNLRAFFYSNGDKPKKDEVY
LNLVLEYVPETVYRASRHYAKLKQTMPMAYIKLYMYQLMRSLAYIHSIGICHRDIKPQNL
LLNPPTGVLKLCDFGSAKILVEGEPNVSYICSRYYRAPELIFGATNYTTNIDVWSAGCVM
AELMLGQPLFPGESGIDQLVEIIKVLGTPTREQIKTMNPNYMEHKFPQIKPHPFVKVFRP
RTPPEAIDLISKLLEYTPSARLTAIESMCHPFFDDLKVPDAKMPTGKDLPPLFDFTREEL
SCRPDLIKNLVPAHAEQELLSRGVDVNNFDPIPLDQMRVHLD